To explore the clinical characteristics and the prognosis of the patients with mild symptoms of influenza，and to compare the differences and safety of Chinese and western medical treatment，and to provide reference for the treatment.Methods:A total of 229 patients with mild influenza were randomly divided into the experimental group and the control group.The experimental group received basic treatment with Chinese medicine treatment，control group was treated with basic and western medicine.The demographic indicators，epidemiological history，underlying diseases，body temperature，symptoms，signs，laboratory tests，chest image examination and electrocardiogram(ECG)were observed.Results:The curative rate of the experimental group was slightly higher than that of the control group.In the experimental group，89 cases(83.96%)were cured，17 cases improved(16.04%)； the control group were 79 cases(80.61%)and 19 cases(19.39%)respectively，the total effective rate was 100%.None of the two groups were transferred to severe or dead.As for the antipyretic effect and completely antifebrile time comparison，the results of the experimental group were shorter than that of the control group，respectively with （3 266.95±1 236.79） and （3 346.25±1 384.12），and （3 805.53±1 546.90） and （3 892.60±1 709.02）.At third days，the rate of relieving rate of respiratory symptoms in the experimental group was higher than that of the control group，and 23.3% vs 13.72%.In the study，5 cases of adverse events were reported，including 3 cases(2.97%)in experimental group and(2.06%)in control group.There was no significant difference between the two groups.The inspection procedure had the same cost，after 5 days’ treatment，the Chinese medicine decoction cost(for the small package of Chinese medicinals，including the brewing)131.78 yuan/case，domestic oseltamivir 168 yuan/case and foreign oseltamivir 264.97 yuan/case.The experimental group cost significantly less than the control group.Conclusion:Chinese medicine has similar efficacy with oseltamivir in treatment of mild influenza，and can also relieve fever and respiratory symptoms，and also is cheap and easy to access.