To discuss the efficacy of catgut implantation at acupuncture point on insomnia with Syndrome of Phlegm-heat attacking internally.Methods:Seventy-five cases of insomnia with Syndrome of Phlegm-heat attacking internally were divided into 3 groups randomly:25 cases in the catgut implantation at acupuncture point therapy group，24 cases in the acupuncture therapy group and 26 cases in the oral medication group respectively，in which they were therapeutically evaluated according to the Pittsburgh sleep quality index(PSQI)scores and syndrome-classification quantitative scores.Results:The sleep quality of insomniacs was effectively improved in both of the 2 groups.The aggregate score of improving sleep quality of the patients in the catgut implantation at acupuncture point therapy group was superior to that of the acupuncture therapy group(P<0.05).The improvement in aggregate score of the catgut implantation at acupuncture point therapy group was close to that of the oral medication group，and sleep quality and daytime function of the former group were better than those of the oral medication group(P<0.05)； however，improvement in sleeping time was not as good as that of the oral medication group(P<0.05).The syndrome improvement in the catgut implantation at acupuncture point therapy group was similar to that of the acupuncture therapy group and they were all more effective than the oral medication group(P<0.05).The total effective rate of the catgut implantation at acupuncture point therapy group was close to that of the oral medication group.In the follow-up visit，which was one month after the treatment，PSQI score improvement and syndrome improvement of the catgut implantation at acupuncture point therapy group were better than those of the acupuncture therapy group，while the oral medication group was the worst in the comparison(P<0.05)，and the total effective rate of the catgut implantation at acupuncture point therapy group and the acupuncture therapy group was superior to that of the oral medication group(P<0.01).Conclusion:The curative effect of the catgut implantation at acupuncture point therapy on insomnia with syndrome of phlegm-heat attacking internally was similar to taking the oral drugs(Estazolam Tablets).With rare adverse reactions，its duration of curative effect was better than the oral drugs and worth of being generalized in clinic.