| 引用本文:李坚.养心氏治疗冠心病心绞痛伴焦虑症的疗效观察[J].世界中医药,2016,(10):. |
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| 养心氏治疗冠心病心绞痛伴焦虑症的疗效观察 |
| Observation of Clinical Effect of YangXinShi Tablets onTreatment of Coronary Heart Disease Angina Pectoris together with Anxiety Neurosis |
| 投稿时间：2016-09-07 |
| DOI：10.3969/j.issn.1673-7202.2016.10.009 |
| 中文关键词: 养心氏片 冠心病 焦虑症 心绞痛 汉密顿焦虑量表 |
| English Keywords:YangXinShi tablet Coronary heart disease Anxiety neurosis Angina pectoris Hamilton anxiety scale |
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| 中文摘要: |
| 目的:评价养心氏片治疗冠心病心绞痛伴焦虑症的临床疗效。方法:将诊断为冠心病心绞痛伴焦虑症的86例患者随机分为对照组(常规西药治疗)和观察组(常规西药治疗+养心氏片),每组43例,1个疗程为12周。观察比较2组的心绞痛症状、LVEF、hs-CRP、NT-proBNP、汉密顿焦虑量表(HAMA)和不良反应。结果:治疗后,1)观察组心绞痛症状改善的总有效率为95.35%,高于对照组的83.72%,差异有统计学意义(P<0.05);2)观察组LVEF为(55±7.4)%,高于对照组的(51±5.4)%(P<0.05);3)观察组hs-CRP为(1.07±0.21)mg/L,低于对照组的(1.32±0.23)mg/L(P<0.05);4)观察组NT-proBNP为(573±122)ng/L,低于对照组的(807±138)ng/L(P<0.05);5)观察组HAMD平均得分为(7.5±1.6),低于对照组的(13.8±2.9)(P<0.05);6)观察组不良反应发生率为2.32%,低于对照组的18.60%(P<0.05)。结论:养心氏片联合西药治疗冠心病心绞痛伴焦虑症比常规西药治疗效果更佳。 |
| English Summary: |
| To evaluate the effects of YangXinShi tablets on coronary heart disease angina pectoris together with anxiety neurosis. Methods:A total of 86 patients who were diagnosed as coronary heart disease angina pectoris together with anxiety neurosis in the hospital were randomly divided into YangXinShi group (conventional western medicine and YangXinShi tablets treatment) and control group (conventional western medicine treatment),43 cases in each group treated for 12 weeks. After treatment,the clinical symptoms of angina pectoris,LVEF,hs-CRP,NT-proBNP,HAMAand adverse reactions of all patients were detected. Results:After treatment,1) the total effective rate of improving angina pectoris in YangXinShi group (95.35%) was higher than that of the control group (83.72%) and the difference was statistically significant (P<0.05); 2) the LVEF in YangXinShi group (55±7.4)% was higher than that of the control group (51±5.4)%,P<0.05; 3) the hs-CRP in YangXinShi group (1.07±0.21) mg/L was lower than that of the control group (1.32±0.23) mg/L,P<0.05; 4) the NT-proBNP in YangXinShi group (573±122)ng/L was lower than that of the control group (807±138)ng/L,P<0.05; 5) the HAMA average score in YangXinShi group (7.5±1.6) was lower compared with that of the control group (13.8±2.9),P<0.05; 6) the incidence of adverse reactions in YangXinShi group (2.32%) was lower than that of the control group (18.60%),P<0.05.Conclusion:YangXinShi tablets together with western medicine on coronary heart disease angina pectoris complicated with anxiety neurosis was better than the conventional western medicine treatment. |
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