世界中医药

目的：观察红花如意丸配合穴位埋线治疗月经不调临床疗效。方法：126例月经不调患者随机分成治疗组和对照组，每组63例，对照组给予常规雌激素、孕激素周期治疗，连续治疗3个月经周期，治疗组服用红花如意丸5丸／次，2次／d，服用3个月经周期，在此基础上配合穴位埋线，2周／次，4周1个疗程，连续3个疗程。在治疗结束后比较2组患者临床疗效、血清雌二醇(Estradiol2，E2)、卵泡刺激素(Follicle Stimulating Hormone，FSH)、黄体生成素(Luteinizing Hormone，LH)、前列腺素E2（prostaglandinE2，PGE-2）和前列腺素2a（prostaglandin2a，PGF-2a）、β-内啡肽（β-endorphin，β-EP）水平。结果：对照组总有效率为85.7%,治疗组的总有效率为93.7%,2组治疗后血E2、FSH、LH、PGE-2、PGF-2a、β-EP水平与治疗前比较，差异有统计学意义(P<0.05)。结论：红花如意丸配合穴位埋线能够有效的治疗月经不调，安全可靠，值得临床推广。

English Summary:

To observe the clinical effect of Safflower Ruyi Pill combine with catgut embedment in acupoint in the treatment of menstrual disorders.Methods:A total of 126 patients were divided two groups by random number table.The control group was treated with estrogen and progesterone for three menstrual cycles.The observation group was treated with Safflower Ruyi Pill combine with catgut embedment in acupoint,two group were treated once a day,and the treatment of Safflower Ruyi Pill was 5 pills/time and twice a day for three menstrual cycles,at the same time combine with catgut embedment in acupoint 2 weeks a time and 4 weeks as a course for three courses.The clinical efficacy and serum estradiol (estradiol,E2),follicle stimulating hormone,(FSH),luteinizing hormone,luteinizing hormone (LH),prostaglandinE2(PGE-2),prostaglandin2a (PGF-2a),β-endorphin (β-EP) level differences of the two groups at the end of the treatment.Results:The effective rate was 85.7% in the control group and 93.7% in the observation group.The differences of the two groups in blood E2,FSH,LH,PGE-2,PGF-2a and β-EP level were statistically significant after treatment (P<0.05).Conclusion:The effect of Safflower Ruyi Pill combined with catgut embedment in acupoint therapy on menstrual disorders is significant and safety,which is worthy of clinical promotion.

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