| 引用本文:韩丽1,2，白桦3，王磊2，杨佳2，刘钧天2,4，王晶5，黄畅2，刘耀萌2，邢敏2，潘秀颉6，赵百孝2.临床诊室浓度的艾烟暴露12周对Wistar雄性大鼠尿常规的影响[J].世界中医药,2016,(10):. |
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| 临床诊室浓度的艾烟暴露12周对Wistar雄性大鼠尿常规的影响 |
| The Effects of Twelve-week Moxa Smoke Exposure on Urinary Parameters in Male Wistar Rats |
| 投稿时间：2016-01-27 |
| DOI：10.3969/j.issn.1673-7202.2016.10.047 |
| 中文关键词: 艾烟 艾灸 遮光率 尿常规 尿 |
| English Keywords:Moxa Smoke Moxibustion Shading Rate Urinary Parameters Urine |
| 基金项目:国家重点基础研究发展计划(“973”计划)项目(编号:2009CB522906);国家自然科学基金项目(编号:81373730;81403449;81574068);国家国际科技合作专项项目(编号:2011DFA31370) |
| 作者 | 单位 | | 韩丽1,2，白桦3，王磊2，杨佳2，刘钧天2,4，王晶5，黄畅2，刘耀萌2，邢敏2，潘秀颉6，赵百孝2 | 1 北京中医药大学中医学养生研究所,北京,100029
2 北京中医药大学针灸推拿学院,北京,100029
3 西安市中医院,西安,710021
4 北京中医药大学附属护国寺中医医院,北京,100035
5 世界中医药学会联合会,北京,100101
6 中国人民解放军军事医学科学院,北京,100039 |
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| 中文摘要: |
| 目的:观察临床诊室浓度的艾烟暴露12周对Wistar雄性大鼠尿常规影响。方法:应用全自动动式染毒柜,艾烟的浓度以遮光率SR表示。将Wistar雄性大鼠48只随机分成4个艾烟浓度梯度组(n=12):对照组(C,SR 0%)、低浓度组(L,SR 0.4%)、中浓度组(M,SR 2%)、高浓度组(H SR 15%),分别为无艾烟组,1,3，9倍于临床浓度艾烟组。暴露200 min/d,5 d/周,连续暴露12周。应用尿干化学分析法检测大鼠尿常规等指标。结果:艾烟暴露各组尿的颜色、SG、PRO、GLU、BLD、URO和BIL检查等均未见显著改变(P>0.05)。结论:临床诊室浓度的艾烟暴露未对雄性大鼠尿常规指标产生毒性影响。 |
| English Summary: |
| To investigate the effects of the 12-week moxa smoke intervention on urinary parameters in Wistar rats.Methods:An automatic dynamic exposure device was applied for whole-body mode exposure.The moxa smoke concentration was represented by shading rate (SR:x %).Forty-eight male Wister rats were randomly divided into 4 groups (n=12/group):three moxa smoke groups according smoke concentrations (L 0.4%,M 2.0% and H 15%) and one control group (C).Three moxa smoke groups were respectively 1,3,and 9 times the clinical concentration.The exposure lasted for 12 weeks (200 min/d and 5 d/week).After the exposure,urine samples were tested by uric dry chemical analysis method.Results:Compared with C group,no statistically differences in the color,SG,PRO,GLU,BLD,URO,BIL were found in smoke-exposed groups (P>0.05).Conclusion:The 12-week moxa smoke exposure induced no smoke-related toxicity on urinary parameters in male Wistar rats. |
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