世界中医药

目的：探讨茵陈蒿汤加减对ABO母婴血型不合孕妇抗体滴度和免疫功能的影响。方法：选取2014年1月至2014年12月确诊为ABO母婴血型不合的128例孕妇纳入研究对象，采用随机数字表法分为治疗组和对照组各64例。2组均给予常规对症处理，对照组联合应用茵栀黄口服液治疗，治疗组给予茵陈蒿汤加减治疗，2组孕疗程均为30 d。比较2组孕妇抗体滴度、免疫功能、治疗效果。结果：临床疗效：治疗组总有效率9531%明显高于对照组8281%（χ2=5133，P<005）；血清抗体水平：治疗组血清抗体在1:64及以下8750%明显高于对照组5000%（χ2=19236，P<005）；免疫功能：治疗组CD3+、CD8+数量高于对照组，CD4+计数、CD4+/CD8+比值均低于对照组（t＝2308～11158，P<005）。结论：茵陈蒿汤辨证方有助于降低ABO母婴血型不合孕妇抗体滴度，改善母体免疫功能，提高治疗效果。

English Summary:

To investigate the effects of Virgate Wormwood Decoction on ABO blood group incompatibility titer and immune function in pregnant women.Methods:During 2014 January to December 2014,total 128 cases of pregnant women diagnosed as ABO blood group incompatibility included in the study were randomly divided into observation group and control group by random number table,64 cases in each group.Two groups were given routine symptomatic processing,additionally the control group were treated with Yin Zhi Huang oral liquid while the observation group given modified Virgate Wormwood Decoction for treatment and pregnancy period of treatment of two groups were 30 days.The antibody titer,and the immune function,and the treatment effect were compared between the two groups.Results:As for the clinical efficacy:in observation group,the total efficiency was 95.31%,which was significantly higher than that of the control group’s 82.81% (χ2=5.133,P<005); as for the serum antibody level:in the observation group,the level of serum antibody in 1:64 and below 87.50%,which was significantly higher than that of control group’s 5000% (χ2=19.236,P<005); immune function:CD3+,CD8+ of the observation group were higher than that of the control group,CD4+ counts,the ratio of CD4+/CD8+ were lower than control group (P<005,t＝2.308~11.158).Conclusion:Virgate Wormwood Decoction with syndrome differentiation is beneficial in reducing ABO blood group incompatibility of maternal antibody titer,improving maternal immune function as well as the therapeutic effect.

查看全文查看/发表评论下载PDF阅读器