世界中医药

目的:探讨胰岛素治疗糖尿病过程中配合山药食疗临床效果。方法:选取2014年1月至2015年12月在我院门诊诊治的2型糖尿病患者98例为研究对象,采用随机分组表将患者随机分为研究组和对照组,2组患者均给予胰岛素控制血糖,同时研究组患者给予山药食疗,比较2组患者疗效及治疗前后空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)、空腹C肽(FCP)、餐后2 h C肽(2 h CP)、改良胰岛素抵抗指数(HOMA-IR)、改良胰岛功能指数(HOMA-islet)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL)、高密度脂蛋白胆固醇(HDL)水平。结果:研究组患者治疗总有效率(95.92%)显著高于对照组(75.51%),两者比较差异有统计学意义(P<0.05)。研究组患者中医证候疗效优良率(93.88%)显著高于对照组(75.51%),两者比较差异有统计学意义(P<0.05)。治疗前2组患者FPG、2 hPG、HbA1c、FCP、2 h CP、HOMA-IR、HOMA-islet、TC、TG、LDL、HDL水平比较差异无统计学意义(P>0.05);治疗后研究组患者FPG、2 h PG、HbA1c、HOMA-IR、TC、TG、LDL水平均低于对照组,HDL、FCP、2 hCP、HOMA-islet水平高于对照组,2组比较差异有统计学意义(P<0.05)。结论:胰岛素治疗糖尿病过程中配合山药食疗,采用中西医结合疗法,可有效调节患者血糖、血脂,改善胰岛功能,提高临床疗效。

English Summary:

To investigate the clinical efficacy of insulin associated with Chinese yam diet therapy on diabetes. Methods:Select 98 cases of type 2 diabetes outpatients who received treatment in our hospital from January 2014 to December 2015, and divide them into a study group and a control group randomly. Both of the two groups of patients were treated with insulin to control blood sugar, while the study group were also provided with yam diet, comparing the efficacy and fasting plasma glucose (FPG), 2 h postprandial blood glucose (2 hPG), glycated hemoglobin (HbA1c), fasting C peptide（FCP）、C peptide 2 hours after meal(2 hCP)、improved insulin resistance index（HOMA-IR）,improved islet function index（HOMA-islet）,total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL) levels of both groups before and after the treatment. Results:Patients total effective rate (95.92%) of the study group was significantly higher than that of the control group(75.51%) with statistical significance（P<0.05）. Good rate of development in TCM syndromes in the study group (93.88%) was considerably higher than that of the control group (75.51%), showing statistical significance as well（P<0.05）. Patients’FPG、2 hPG、HbA1c、HOMA-IR、HOMA-islet、TC、 TG、LDL、HDL levels before treatment were compared， with no statistical significance （P>0.05）; After the treatment, FPG, 2 hPG, HbA1c, HOMA-IR, TC, TG, LDL levels of patients in the study group were all lower than those of the control group, while HDL、FCP 、2 hCP、HOMA-islet levels higher（P<0.05）with statistical significance. Conclusion:Insulin associated with Chinese yam diet therapy treatment on diabetes is the integration of Chinese and Western medicine and effectively regulates blood sugar and blood lipids and improves islet function，thus develops clinical efficacy .

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