| 引用本文:王小龙1，徐彬1，周雷1，马俊杰1,2，李智强1，徐增柏1.扶正抗癌方联合化疗治疗胃癌效应观察[J].世界中医药,2016,(12):. |
|
| 扶正抗癌方联合化疗治疗胃癌效应观察 |
| Clinical Curative Effect of Fuzhengkangai Decoction in Stomach Cancer |
| 投稿时间：2016-11-28 |
| DOI：10.3969/j.issn.1673-7202.2016.12.051 |
| 中文关键词: 扶正抗癌方 中医药 化疗 肝胃不和 胃癌 |
| English Keywords:Fuzhengkangai decoction Traditional Chinese medicine Chemotherapy Liver-stomach disharmony Stomach cancer |
| 基金项目:宿迁市科技项目（编号：Z201517）——扶正抗癌方治疗肝胃不和型胃癌临床疗效及机制研究 |
|
| 摘要点击次数: 775 |
| 全文下载次数: 742 |
| 中文摘要: |
| 目的：观察扶正抗癌方联合西药治疗肝胃不和型胃癌疗效及机制。方法：将41例患者胃癌随机分为2组，均给予多西他赛40 mg/m2，第1，8天，静脉滴注1 h，并常规给予抗过敏预处理；奥沙利铂75 mg/m2，第1天，静脉滴注2 h；21 d为1个周期，共化疗2个周期。对照组21例在此基础上加服安慰剂；治疗组20例在上述治疗的基础上加用扶正抗癌方，治疗1个疗程(40 d)。判定疗效，观测临床症状、症状积分、不良反应，及免疫指标等。结果：观察组治疗总有效率显著高于对照组(P<0.05)，免疫功能相关指标优于对照组(P<0.05)，KPS评分(卡氏生活质量评分)显著优于对照组(P<0.05)。结论：扶正抗癌方联合西药治疗肝胃不和型胃癌疗效满意，无严重不良反应，可显著改善免疫功能及生存状况，值得推广应用。 |
| English Summary: |
| To explore the clinical curative effect and mechanism of Fuzhengkangai decoction in stomach cancer.Methods:Fourty-one patients with gastric cancer were randomly divided into two groups, all given Docetaxel 40 mg/m2, on the first and the eighth day intravenous drip for1 h, and an allergy conventional pretreatment；Oxaliplatin 75 mg/m2, 1 day, intravenous drip for 2 h；21 d as a cycle, and there were two chemotherapy cycles. The 21 cases of Control group were provided with extra placebos; The 20 cases of Treatment group were on the basis of above treatment and with Fuzhengkangai decoction for 1 course (40 d). Curative effect, clinical symptoms, symptom integral, adverse reactions, and immune index, etc. were observed.Results:The total effective rate of the observation group was significantly higher than that of the control group (P<0.05), and the related parameters of immune function was better than that of control group (P<0.05), KPS score (carr’s quality of life score) also better (P<0.05).Conclusion:The consequence of Fuzhengkangai decoction combined with western medicine in stomach cancer which is due to liver-stomach disharmony is favorable with no serious adverse reactions, and can significantly improve the immune function and survival condition, whih is worthy of promotion. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
