| 引用本文:张和韡，田甜，赵丹丹，段宇航，高思华，马淑然，张淑静.苏木与扶正药物配伍对C57BL/6小鼠Lewis肺癌生长及转移的影响[J].世界中医药,2016,(12):. |
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| 苏木与扶正药物配伍对C57BL/6小鼠Lewis肺癌生长及转移的影响 |
| The effect of lignum sappan with different tonifying drugs on Lewis lung cancer |
| 投稿时间：2016-03-29 |
| DOI：10.3969/j.issn.1673-7202.2016.12.059 |
| 中文关键词: 苏木 活血化瘀 Lewis肺癌 |
| English Keywords:Lignum sappan Blood circulation Lewis lung carcinoma |
| 基金项目:北京中医药大学2015年度基本科研业务费项目(编号：2015-JYB-JSMS006) |
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| 中文摘要: |
| 目的:观察苏木配伍不同扶正药物对Lewis肺癌生长和转移的影响。方法:建立Lewis肺癌C57BL/6小鼠肿瘤模型,随机分为6组:对照组、苏木组、苏木黄芪组、苏木当归组、苏木附子组、苏木麦冬组,连续灌胃给药21 d。于第21天处死小鼠,观察各组抑瘤率、抑转移率。结果:苏木配伍不同的扶正药物对肿瘤均有抑制作用(P<0.05),苏木当归组、苏木麦冬组、苏木附子组抑制肿瘤效果优于苏木(P<0.05)。结论:苏木配伍扶正药物可抑制肿瘤生长和转移。 |
| English Summary: |
| To investigate the effect of lignum sappan with different tonifying drugs on growth and metastasis of Lewis lung cancer(LLC).Methods:Lewis lung carcinoma C57BL / 6 mouse tumor models were randomly divided into six groups: the control group,lignum sappan group,lignum sappan+astragalus group,lignum sappan+Angelica group, lignum sappan+Aconite group,lignum sappan+Liriope group.Continuous oral administration 21 days.Mice were sacrificed on the 21th day.Inhibition rate and suppressing metastasis rate were observed.Results:lignum sappan with different tonifying drugs could inhibit the growth and metastases of LLC (P<0.05)， lignum sappan+Angelica sinensis group, lignum sappan+Liriope group, lignum sappan+Aconite group were better than lignum sappan group.(P<0.05).Conclusion:Drugs compatibility of lignum sappan with tonifying drugs and could inhibit tumor growth and metastasis. |
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