| 引用本文:华海燕，朱海军.针灸对失眠患者的临床效果及体内炎性反应因子水平影响的研究[J].世界中医药,2016,(12):. |
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| 针灸对失眠患者的临床效果及体内炎性反应因子水平影响的研究 |
| Study on Clinical Effect of Acupuncture on Patients with Insomnia and Influence on Levels of In Vivo Inflammatory Factors |
| 投稿时间：2016-04-12 |
| DOI：10.3969/j.issn.1673-7202.2016.12.063 |
| 中文关键词: 针灸 失眠 炎性反应因子 疗效 |
| English Keywords:Acupuncture Insomnia Inflammatory cytokines Curative effect |
| 基金项目:江苏省卫生厅预防医学课题（编号：Y2013081） |
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| 中文摘要: |
| 目的：观察针灸疗法在治疗失眠方面的临床疗效。方法：选取2015年3月至2015年12月收住我科的失眠患者90例，随机分成对照组和治疗组，各45例。对照组采取三唑仑口服，1次/d，1次3片，睡前口服，为期2周，14 d。治疗组采取针刺主穴取肝俞、心俞穴、脾俞穴、肺俞穴、肾俞、期门、晴明穴、涌泉穴，1次/d，每周4次，连续治疗2周。结果：1）治疗后治疗组有效率86.66％，对照组有效率68.88％，2组有效率比较（P<0.05），差异有统计学意义。2）2组患者治疗前后PSQI各因子及总分比较，（P<0.05），差异有统计学意义；2组间在睡眠质量、睡眠时间、日间功能障碍及总分方面等的比较，治疗组低于对照组（P<0.05），差异有统计学意义，治疗组的疗效明显比对照组更好。3）2组患者在治疗前，检测的血清白介素-1β（Interleukine-1 Beta，IL-1β）、白介素-6（Interleukine-6,IL-6）、5-羟色胺（5-hydroxytryptamine，5-HT）及肿瘤坏死因子-α（Tumor Necrosis Factor α,TNF-α）含量比较，差异无统计学意义，而组间治疗后比较，治疗组明显低于对照组（P<0.05），治疗组疗效比对照组好。结论：失眠疗法治疗失眠方面有显著的临床效果，且不良反应及成本也较低，值得推广。 |
| English Summary: |
| To observe clinical efficacy of acupuncture in the treatment of insomnia．Methods:Ninety patients with insomnia admitted in the department from March 2015 to December 2015 were selected and randomly divided into the control group and observation group, with 45 cases in each. The control group received oral estazolam, once a day with one tablet before sleep for two weeks. The observation group had acupuncture with the main points of Ganshu (BL18)， Xinshu (BL15)， Pishu (BL20), Feishu (BL13), Shenshu (BL23), Qimen (LR14), Jingming (BL1) and Yongquan (KI1), once a day and 4 times a week, for 2 weeks. Results:1) The effective rate of the observation group was 86.66% and that of the control was 68.88%, showing statistically significant differences (P<0.05). 2) PSQI each factor and total score between the two groups before and after treatment showed statistically significant difference (P<0.05). Sleep quality, sleep duration, daytime dysfunction and other indexes of the total score of the observation group was lower than those of the control group (P<0.05), which indicated the statistically significant difference. The efficacy of the treatment group was significantly better than that of the control group. 3) IL-1β, IL-6, 5-HT and TNF-α between the two groups before the treatment showed no statistically significant differences but those of the treatment group were significantly lower with better efficacy after the treatment compared with the control group 2 (P<0.05). Conclusion:The therapy of acupuncture in Insomnia has a significant clinical effect with low cost but no obvious adverse effects, which is worth promoting. |
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