| 引用本文:张兵.补肾活血化瘀法对子宫内膜异位症血流变学及性激素水平的影响[J].世界中医药,2017,(01):. |
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| 补肾活血化瘀法对子宫内膜异位症血流变学及性激素水平的影响 |
| Effect of Kidney-reinforcing Blood-activating and Stasis-removing Method on Blood Rheology and Sex Hormone Levels in Endometriosis |
| 投稿时间：2016-12-08 |
| DOI：10.3969/j.issn.1673-7202.2017.01.019 |
| 中文关键词: 补肾活血化瘀法 子宫内膜异位症 血流变学 性激素 红细胞免疫功能 |
| English Keywords:Kidney-reinforcing Blood-activating and Stasis-removing Method Endometriosis Blood rheology Sex hormone Red blood cell immune function |
| 基金项目:国家自然科学基金项目(编号:30930113)——葛根素与子宫内膜异位症雌激素受体结合后作用通路模式及其靶向性机制研究 |
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| 中文摘要: |
| 目的:探讨补肾活血化瘀法对EMT患者血流变学、血清性激素、红细胞免疫功能及血生化指标水平的影响。方法:选取2014年2月至2016年1月本溪钢铁总医院收治的子宫内膜异位症患者86例,随机分为治疗组与对照组,各43例。治疗组给予补肾活血化瘀法治疗,对照组采用孕三烯酮胶囊治疗。观察并比较2组患者血流变学、血清性激素、红细胞免疫功能及TNF-α、PGF2α水平变化。结果:治疗后2组红细胞聚集指数、全血还原黏度、红细胞沉降率及血浆比黏度,P、E2及PRL水平,TNF-α及PGF2α水平均显著降低(P<0.05或P<0.01),且治疗组显著低于对照组(P<0.05或P<0.01);治疗后2组RC3bR(%)显著升高,RIcR(%)显著降低(P<0.05或P<0.01),且2组间比较差异有统计学意义(P<0.05或P<0.01)。结论:补肾活血化瘀法能显著改善EMT患者机体血循环状态,并能调节其内分泌功能,效果显著,安全可靠。 |
| English Summary: |
| To explore the effect of the method of Kidney-reinforcing Blood-activating and Stasis-removing Method on blood rheology，serum sex hormones，red blood cell immune function and blood biochemical indexes in EMT patients.Methods:A total of 86 cases of endometriosis were randomly divided into treatment group and control group，43 cases in each group.The treatment group was given Kidney-reinforcing Blood-activating and Stasis-removing treatment，the control group treated with Gestrinone Capsules.Observation and comparison of two groups of patients′ blood rheology，serum sex hormones，red blood cell immune function and TNF-alpha，PGF2 alpha level changes were performed before and after the treatment.Results:After treatment，two groups′ red cell aggregation index，whole blood reduced viscosity，plasma viscosity and erythrocyte sedimentation rate，P，E2 and PRL levels，TNF-alpha and PGF2 levels were significantly lower (P<0.05 or P<0.01)，and the treatment group had significantly better results than the control group (P<0.05 or P<0.01); After treatment，the RC3bR(%) in two groups increased significantly，while RIcR (%)decreased significantly (P<0.05 or P<0.01)，and the differences between the two groups were significant (P<0.05 or P<0.01).Conclusion:Kidney-reinforcing Blood-activating and Stasis-removing Method can significantly improve the blood circulation of EMT patients，and regulate the endocrine function，with remarkable effect，safety and reliablility. |
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