To search literature about TCM treatment for myasthenia gravis and to evaluate literature quality, providing evidence and reference for TCM clinical diagnosis and treatment guideline of myasthenia gravis. Methods:Literature was retrieved by computer search and manual search in China Academic Journal (CNKI), Chinese Biomedical Literature Database (CBM), VIP database, Pubmed and other databases. Noteexpress 2.8 software was used for reduplication of literature of myasthenia gravis. Modified Jadad scale, AMSTAR scale and MINORS entry literature quality assessment rating scale were applied for literature quality evaluation. Literature was graded according to Reference for Evidence-Based Clinical Evidence Grading. Results:A total number of 372 journals were finally included. The quality literature was not high after assessment. The recommended grading level was IV with a total number of104 articles and 268 articles were recommended for grade V. Conclusion:TCM clinical diagnosis and treatment guidelines for myasthenia gravis still need to be highly developed and revised. Randomized and controlled studies with large sample are further needed. Scientific and appropriate use of experience from famous physicians is also required at the same time.