世界中医药

目的:观察二陈四物汤加减治疗脂肪肝的临床疗效。方法:选取2009年1月至2015年12月我院门诊及住院非酒精性脂肪肝患者124例,随机分为治疗组和对照组,2组患者均予维生素E 10 mg/次,3次/d,口服,联合东宝肝泰片基本治疗,治疗组同时加用二陈四物汤加减治疗,1个月为1个疗程,治疗3个疗程以后,观察2组治疗前后的症状体征改善情况、超声影像以及总疗效,并检测肝功能和血脂变化情况。结果:治疗组与对照组的治疗后的总有效率分别为(85.5%)和(66.1%),2组间疗效差异有统计学意义(P<0.05);2组治疗后与治疗前相比,患者的治疗前症状体征、肝功能、血脂指标和超声影像均有显著改善,但治疗组效果显著优于对照组(P<0.05)。结论:二陈四物汤对非酒精性脂肪肝有较好的治疗作用,可从根本上改善患者体内的脂肪肝含量,有效的降低血脂、血压状况,明显提高患者的生活水平,降低非酒精性脂肪肝的患病率,值得被推广。

English Summary:

To observe the clinical curative effect of Modified Two Chen Four Ingredients Decoction in the treatment of fatty liver. Methods:A total of 124 patients of Nonalcoholic Fatty Liver in our hospital during January 2009 to December 2009 were randomly divided into treatment group and control group. Two groups received basic treatment of vitamin E 10 mg tid Po and Dongbao Pill. Treatment group at the same time received Two Chen Four Ingredients Decoction. One month was regarded as a course. After 3 treatment courses, the signs and symptoms, ultrasound images, the total curative effect, liver function and blood lipid changes of two groups were observed before and after treatment. Results:After treatment, total effective rate of treatment group and control group were 85.5% and 66.1% respectively, differences between two groups was statistically significant (P=0.0035); The signs and symptoms, ultrasound images, the total curative effect, liver function and blood lipid changes of two groups were improved after the treatment, but the treatment group had significantly better effect (P<0.05). Conclusion:Two Chen Four Ingredients Decoction is effective in nonalcoholic fatty liver disease, which can fundamentally reduce the content of fat in liver, as well as blood fat, blood pressure condition, and improve quality of life, and reduce the rate of nonalcoholic fatty liver disease. Therefore, it is worthy of promotion.

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