| 引用本文:潘虹虹，王小曼，牛向馨.中医药辨证治疗脾虚型青春期功能失调性子宫出血51例临床近远期疗效研究[J].世界中医药,2017,(02):. |
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| 中医药辨证治疗脾虚型青春期功能失调性子宫出血51例临床近远期疗效研究 |
| TCM Differential Treatment on Puberty Dysfunctional Uterine Bleeding of Spleen Deficiency Type：A Short and Long Term Clinical Efficacy Research of 51 Cases |
| 投稿时间：2016-05-20 |
| DOI：10.3969/j.issn.1673-7202.2017.02.026 |
| 中文关键词: 中医药 脾虚型 青春期 功能失调性子宫出血 疗效 |
| English Keywords:Chinese medicine Spleen Deficiency Puberty Dysfunctional uterine bleeding Efficacy |
| 基金项目:海南省中医药管理局资助基金项目（编号：琼卫2012PT-107） |
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| 中文摘要: |
| 目的：探讨中医药辨证治疗脾虚型青春期功能失调性子宫出血疗效，以期丰富治疗方法。方法：选取2011年12月至2013年11月102例脾虚型青春期功能失调性子宫出血患者为研究对象，分成2组，对照组51例，采用黄体酮胶囊口服，观察组51例，采用益气化瘀方和补肾固冲方治疗，观察治疗后相关指标变化情况。结果：对照组治愈率19.61%、总有效率84.31%，观察组治愈率41.18%、总有效率96.08%，观察组在治愈率和总有效率上显著高于对照组(P<0.05)；2组治疗前后在血红蛋白和纤维蛋白原上比较无统计学意义（P>0.05），血栓素A2上治疗后较治疗前显著下降（P<0.05），血浆P浓度、D-二聚体治疗后较治疗前显著提高（P<0.05），观察组治疗后在血栓素A2、D-二聚体较对照组治疗后比较无统计学意义（P>0.05），在血浆P浓度升高较对照组有统计学意义(P<0.05)；观察组止血时间较对照组明显缩短，2组比较有统计学意义（P<0.05），对照组1年内再出血发生率、不良反应发生率分别为23.53%、9.8%，观察组1年内再出血发生率、不良反应发生率分别为11.76%、1.96%，观察组明显低于对照组，2组比较有统计学意义(P<0.05)。观察组患者在阴道流血、流血次数、小腹疼痛、心悸气短、面色无华单项临床症状总疗效均明显高于对照组，组间比较差异有统计学意义（P<0.05）。结论：中医药辨证治疗脾虚型青春期功能失调性子宫出血疗效确切。 |
| English Summary: |
| To investigate the efficacy of TCM differential treatment on puberty dysfunctional uterine bleeding of spleen deficiency type and to enrich treatment.Methods:Taking 102 adolescent patients with dysfunctional uterine bleeding spleen type hospitalized from December 2011 to November 2013，all were divided into two groups，51 cases in the control group with oral application of progesterone capsules，51 cases in the observation group with Yiqihuayu formula and Bushenguchong decoction treatment，and changes in relevant indicators were observed after treatment.Results:The cure rate of control group was 19.61%，the total efficiency 84.31%，and the cure rate of observation group was 41.18%，the total efficiency 96.08%.The observation group had significantly higher cure and total efficiency rate (P<0.05); two groups before and after treatment in hemoglobin and fibrinogen was not statistically significant (P>0.05)，and after treatment the thromboxane A2 significantly decreased (P<0.05)，plasma p concentrations and D-dimer after treatment increased (P<0.05).For the observation group，the difference of thromboxane A2 and D-dimer before and after treatment was not significant (P>0.05)，but p plasma concentrations increased more significantly (P<0.05); hemostasis time of observation group was significantly shorter than the control group (P<0.05).As to 1 year rebleeding rate and incidence of adverse reactions rate，the control group 23.53% and 9.8%，respectively，the observation group 11.76% and 1.96%,those of the observation group was significantly lower than those of the control group，and the difference was significant (P<0.05).In the observation group，total effect on individual symptoms like were vaginal bleeding，bleeding times，abdominal pain，palpitations，shortness of breath，were significantly higher than the other group，and the difference between groups was statistically significant (P<0.05).Conclusion:TCM differential treatment on puberty dysfunctional uterine bleeding of spleen deficiency type has clear efficacy. |
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