Climacteric syndrome is a common disease for women during the menopause. Autonomic nervous system disorders or psychological changes associated with nerve symptoms may occur with the change of hormones and even affect daily life,work or mental state of the menopausal women. Prof. Liu Yanfeng who worked in Dongzhimen Hospital of Beijing University of Chinese Medicine,inherited academic thoughts of famous gynecologic expert,Prof. Xiao Chengzong and proposed menopause onset “maladaptive” hypothesis with his own clinical practice. He believes that imbalance between heart-yang and kidney-yin might be the critical pathogenesis and treatment for climacteric syndrome should accord with restoring normal coordination between heart and kidney and harmonizing yin and yang.