世界中医药

基金项目:国家中医药管理局国家中医临床研究基地业务建设科研专项课题（编号：JDZX2012103）——中医药治疗小儿支原体肺炎疗效评价研究；上海市市级医院新兴前沿技术联合攻关项目（编号：SHDC12014110）——中西医结合治疗儿童支原体肺炎诊疗方案规范化研究；上海市科委基金项目：清肺通络汤治疗儿童肺炎支原体肺炎疗效评价（编号：14401930300）；上海市市属博士点学科建设基金（编号：B201402）

作者	单位
姜之炎，王雪峰，王立宁，秦艳红，许华，白晓红，姜永红，肖臻，林燕	上海中医药大学附属龙华医院，上海，200032

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中文摘要:

目的：通过开展中西医结合综合治疗方案治疗小儿支原体肺炎的临床疗效评价研究，评价中医药在小儿支原体肺炎治疗中的有效性和安全性。方法：本临床试验为多中心、前瞻性队列研究，按照治疗方案的不同，自然形成单纯西医治疗组（西医组）和中西医结合治疗组（中西医组）。西医组采用阿奇霉素基础治疗，中西医组在基础治疗的同时，结合中医内服外治方案。结果：临床疗效西医组的痊愈率为18.9%，显效率为78.9%，有效率为100%(n=90)，中西医组痊愈率31.9%，显效率76.8%，有效率为100%(n=310)；2组痊愈率比较，差异有统计学意义(P<0.05)；2组显效率和有效率比较差异无统计学意义(P>0.05)。结论：中西医组疗效明显优于西医组。

English Summary:

To evaluate the efficacy of combined treatment to mycoplasma pediatric pneumonia and the effectiveness and safety of TCM. Methods:The clinical experiment is a multi-centered, prospective cohort study. According to different treatments, western medicine group and TCM integrated with western medicine group were naturally set up. Western medicine treatment group were given azithromycin. While on this basis, integrated group was treated by TCM internal and external medication. Results:The cure rate of western medicine group was 18.9%, significant efficiency was 78.9%, and the effective rate 100% (n=90). The cure rate of the integrated group was 31.9%, significant efficiency rate 76.8%, and the effective rate 100% (n=310 ). Cure rate between the two groups has statistically significant difference (P<0.05). However, no significant difference exist in regards to significant efficacy rate and effective rate between the two groups (P>0.05). Conclusion:Intergrated Chinese Medicine with Western Medicine has higher efficacy rate.

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