| 引用本文:薛银萍1，李莲2，张冲3.逍遥丸对亚健康-免疫-内分泌系统的影响[J].世界中医药,2017,(04):. |
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| 逍遥丸对亚健康-免疫-内分泌系统的影响 |
| Effect of Xiaoyao Pill on Subhealth-Immune-Endocrine System |
| 投稿时间：2016-07-05 |
| DOI：10.3969/j.issn.1673-7202.2017.04.013 |
| 中文关键词: 逍遥丸 亚健康 内分泌 免疫功能 |
| English Keywords:Xiaoyao Pill Sub-health Endocrine Immune function |
| 基金项目:2011年石家庄市科学技术研究与发展指导计划课题（第一批）（编号：11146933） |
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| 中文摘要: |
| 目的：探讨方剂逍遥丸对亚健康人群的治疗作用，并分析对其免疫功能及内分泌系统的影响。方法：随机选取2014年11月至2016年2月，于我院就诊并确诊为肝郁脾虚型亚健康患者57例，均将其纳入治疗组，予以口服中成药逍遥丸治疗，并在治疗前后对患者进行疲劳评定量表(FAI)及焦虑自评量表（SAS）测定，同时检测其血清中免疫球蛋白（IgA）、T淋巴细胞（CD3+、CD4+）、血浆去甲肾上腺素（NE）、肾上腺素(E)在治疗前后的变化，并将其与前来我院体检的健康成年人志愿者进行对照。结果：经过治疗后，治疗组的疲劳评分明显降低(P<0.05)，且其血清中的IgA、CD3+、CD4+、NE水平均得到不同程度的提高，其中CD3+、CD4+提高较为显著(P<0.05)，且E显著降低(P<0.01)。结论：逍遥丸能有效调节亚健康人群的内分泌水平，并提高人体的免疫能力。 |
| English Summary: |
| To explore the therapeutic effect of Xiaoyao Pill on the sub-healthy people and to analyze its effect on immune function and endocrine system. Methods:Fifty-seven sub-healthy patients diagnosed with liver qi stagnation type who had treatment in the hospital from November 2014 to February 2016 were selected and included into the treatment group，treated with oral Chinese patent medicine Xiaoyao Pill. Fatigue assessment instrument(FAI) and self-rating anxiety scale(SAS) were applied for assessment and changes in serum level of immunoglobulin A (IGA)，T lymphocytes (CD3+，CD4+)，plasma norepinephrine (NE)，epinephrine (E) were detected before and after the treatment and physical examination of healthy adult volunteers were compared as the control group. Results:After treatment，fatigue scores in the treatment group decreased significantly (P<0.05). The level of serum IgA，CD3+，CD4+，NE level improved to some degree and CD3+，CD4+ increased more significantly (P<0.05). E significantly reduced (P<0.01). Conclusion:Xiaoyao Pill can effectively regulate the endocrinal level of sub-healthy people and improve the immune function of the body. |
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