The global ecological suitability analysis was carried out in this study for providing essential data for suitable producing regions of agilawood artificial domestication，thereby to implement resource protection and effective use of this medicinal material.Methods:Global geographic information system for medicinal plant(GMPGIS)was applied to process cluster analysis of Gilg real estate areas，the main producing areas and wild distribution regions of ecological factors of collected Aquilaria sinensis(Lour.)，which containing 94 district sampling points.Results:The most suitable ecological region was China，mainly in Guangdong，Guangxi，Hainan，Yunnan and Fujian provinces.Brazil，Laos and Vietnam were also had the reasonable ecological areas for Aquilaria sinensis producing.Conclusion:GMPGIS can show essential data for suitable producing regions of agilawood cultivation，which also provide scientific basis for resource protection，artificial domestication and standardized cultivation with high quality of agilawood.