In order to ensure the sustainable utilization of the natural resources of Amomum villosum Lour.，the global ecological suitability analysis was carried out by Global geographic information system for medicinal plant(GMPGIS).Methods:A total of 108 distribution sites were collected and put into the system.Seven ecological factors were made cluster analysis to predict the suitable ecological region and potential artificial cultivation area.Results:A total area of about 4 400 000 square kilometers was found suitable for planting Amomum villosum globally.In addition to China，Brazil，Congo and other 56 countries or regions also had ecological conditions for Amomum villosum growth.Guangdong，Guangxi，Yunnan and Fujian were the main producing areas in china.Conclusion:GMPGIS provides scientific guidance for the global artificial cultivation of Amomum villosum.