To discuss the effect analysis based on six-channel pattern identification treating solitary elderly diabetic depression.Methods: Two hundreds patients with solitary elderly diabetic depression were selected,which was in our hospital from September 2008 to December 2012. According to the treatment, patients were divided into a pattern identification group and a control group, 100 cases in each.In the control group, patients were given regular intervention, while the pattern identification group extra six-channel pattern identification treatment, both followed up for 6 months. Hamilton anxiety scale (HAMA) was used to assess the state of anxiety, Hamilton depression scale (HAMD) the depression, Morisky medication adherence questionnaire (MMAS-8) compliance,and all patients'results of fasting blood glucose before and after the intervention, 2 h postprandial blood glucose level and anxiety and depression before intervention after 1, 3 and 6 months'intervention. Results: In pattern identification group, patients'fasting blood glucose, 2 h postprandial blood glucose level after intervention were significantly lower than those of the control group, and the former had higher MMAS-8 score (P<0.05); in pattern identification group, HAMA and HAMD scores after 1, 3 and 6 months' intervention were significantly lower than those of the control group, with significant difference (P<0.05).Conclusion:Based on six-channel pattern identification, the solitary elderly diabetic depression patients'blood sugar levels and medication compliance can be improved, and it can also reduce anxiety and depression,It is worth for further clinical promotion.