世界中医药
文章摘要
引用本文:陈剑峰,薛书峰,段卡丹,王静.丹红注射液治疗缺血性心肌病急性心力衰竭的对照研究[J].世界中医药,2017,(05):.  
丹红注射液治疗缺血性心肌病急性心力衰竭的对照研究
Clinical Controlled Study on Danhong Injection in the Treatment to Acute Heart Failure Caused by Ischemic Cardiomyopathy
投稿时间:2016-12-30  
DOI:10.3969/j.issn.1673-7202.2017.05.029
中文关键词:  丹红注射液  缺血性心肌病  急性心力衰竭  预后
English Keywords:Danhong injection  Ischemic Cardiomyopathy  Acutely Decompensated Heart Failure  Prognosis
基金项目:
作者单位
陈剑峰,薛书峰,段卡丹,王静 郑州大学附属洛阳中心医院心内科,洛阳,471000 
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中文摘要:
      目的:探讨丹红注射液在缺血性心肌病急性失代偿性心力衰竭(Acutely Decompensated Heart Failure,ADHF)患者的疗效及安全性。方法:选取2015年5月至2016年7月经郑州大学附属洛阳中心医院心内科治疗的缺血性心肌病ADHF患者100例,采用随机对照研究方法分为治疗组和对照组,每组50例,2组患者均采用标准化药物治疗,在此基础上治疗组给予丹红注射液,检测2组患者治疗前后脑钠肽(BNP),每搏输出量(SV),左室射血分数(LVEF)等心功能指标,观察治疗后心血管病死率、再次心衰住院率的差别。结果:2组患者一般临床资料差异无统计学意义(P>0.05)。用药治疗1个月后患者BNP、SV、LVEF均有明显改善(P<0.05);治疗组患者1个月后,心血管病死率和再次住院率较对照组显著降低,差异有统计学意义(P<0.05)。结论:丹红注射液可显著改善缺血性心肌病心力衰竭患者的预后。
English Summary:
      To explore the efficacy and safety of Danhong injection in treating Acutely Decompensated Heart Failure(ADHF),which caused by Ischemic Cardiomyopathy.Methods:From May 2015 to July 2016,100 ADHF patients with Ischemic Cardiomyopathy in Luoyang Center Hospital Affiliated to zhengzhou University were randomly divided into treatment group and control group.Fifty patients were in each group.Treatment group was given Danhong injection based on the standardized drug therapy received by both groups.Detecting heart function indexes including brain natriuretic peptide(BNP),stroke volume(SV),left ventricular ejection fraction (LVEF) of the patients in both groups befor and after the treatment.Then,compared the cardiovascular mortality as well as rehospitalization rate with before.Results:General clinical data of two groups had no statiscal significance(P>0.05).After the treatment for a month,the BNP,SV,LVEF of patients improves a lot(P<0.05).Comparing with control group,cardiovascular mortality and rehospitalization rate of treatment reduced obviously,and the difference between two groups had statiscal significance(P<0.05).Conclusion:Danhong injection improved the prognosis of ADHF patients with Ischemic Cardiomyopathy observably.
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