To observe the efficacy of ginger moxibustion on diarrhea-type irritable bowel syndrome (D-IBS) and the changes on proportion of cocci and bacilli. Methods:Thirty patients were treated by ginger moxibustion on Shengue for 1 months, once per day. The monitored indexes included IBS-SSS score and proportion of cocci and bacilli. Results:The IBS-SSS scores before and after treatment were 352.17±92.50 and 70.83±59.42. After treatment, the score was significantly lower than that before treatment（P<0.001，t=20.570）; The proportion of bacilli in fecal smears increased after treatment（P<0.001，t=-6.968）.Conclusion:Ginger moxibustion on Shengue can effectively improve the patient's clinical symptoms, the IBS-SSS score, and the proportion of bacilli in fecal smears.