世界中医药

目的:观察热敏灸治疗癌性贫血的临床疗效,为进一步的推广热敏灸应用奠定临床基础。方法:在患者的知情同意下,选取2015年1月至2016年12月中国中医科学院广安门医院南区门诊及病房共65例癌性贫血患者,按随机数字表法随机划分为2组,剔除脱落患者4例,观察组30例,对照组31例。2组患者均行常规治疗,包括:EPO治疗或铁剂、叶酸、维生素B12等治疗。观察组在对照组治疗基础上配合热敏灸治疗,1次/d,3 d后治疗3次/周,治疗周期1个月。分别于治疗前、治疗后评定患者红细胞、血红蛋白水平,并分别于治疗结束、疗后1个月进行MDASI症状量表评价。结果:2组治疗结束后红细胞和血红蛋白水平均较前有一定升高,观察组与对照组比较差异有统计学意义(P<0.05),以观察组为优。临床疗效比较,治疗结束观察组总有效率为60.00%,明显优于对照组的25.81%,差异有统计学意义(P<0.01)。MDASI量表评价,治疗结束和疗后1个月,2组患者症状积分和生活积分均较治疗前减少,观察组更优。其中疗后1月观察组不适症状反应率38.31%,明显低于对照组44.37%(P<0.05),生活积分比较观察组明显优于对照组(P<0.01)。结论:热敏灸能够有效改善癌性贫血程度,并改善患者生活质量,有较好的临床推广应用价值。

English Summary:

To observe the clinical effect of thermal sensitive moxibustion on anemia of cancer and to lay the foundation for the promotion of its clinical application. Methods: Under the patient's informed consent, we selected a total of 65 cases of patients with anemia of cancer, from January 2015 to December 2016 according to the number table and randomly divided them into 2 groups, eliminating 4 cases of shedding, 30 cases in the treatment group, 31 cases in the control group. Two groups were treated with conventional therapy, including: EPO therapy or iron, folic acid, vitamin B12 and other treatment. The treatment group were treated with extra thermal sensitive moxibustion, once per day in the first 3 days, and after that, 3 times per week, for a course of 1 month. Red blood cells, hemoglobin level were evaluated before and after trearment. At the end of treatment and1 month later, MDASI symptom scale was evaluated. Results: After the treatment, f red blood cells and hemoglobin levels of the 2 groups were lower than those before the treatment with statistically significant difference (P<0.05). Comparing the clinical efficacy after treatment, the total efficiency of treatment group was 60%, significantly higher than that of the control group 25.81%, and there was statistically significant difference (P<0.01). As to MDASI scale evaluation, symptom score and life scores of 2 groups were lower than those before treatment, the treatment group better after treatment. One months later after the treatment, discomfort reaction rate of the treatment group was 38.31%, significantly lower than that of the control group 44.37% (P<0.05), and life score was significantly better than that of the control group (P<0.01). Conclusion: Thermal sensitive moxibustion can effectively improve the degree of anemia of cancer and the quality of life of patients, which has good clinical application value.

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