To analyze the changes of error types in the process of checking and dispensing prescriptions of traditional Chinese medicine(TCM) after the introduction of modern information management mode to our hospital for improving clinical curative effect and service. Methods: Sort out the 5066 sheets of prescriptions from clinical diagnosis and treatment at the TCM pharmacy of our hospital from May 2015 to November 2015. And 5 326 copies of prescriptions were also sorted out after the introduction of modern information management mode from January 2016 and June 2016. The types and times of both the prescription dispensing errors were recorded and analysed by statistics. Results: There were 83 cases out of 5066 prescriptions with dispensing errors( error rate: 1.7%) before the implementation of modern information management mode; and after the implementation, 31 cases out of 5 326 prescriptions appeared to have dispensing errors (error rate: 0.6%, χ2=26.702, P<0.05) The frequency of errors before and after the impletation: the occurrance of errors in Chinese patent medicine dropped from 53 cases to 21; and there was a reduction in errors from 32 cases to 10 in Chinese herbal medicine. According to the investigation before and after the intervention, the analysis suggested that the total errors dropped from 85 cases to 31, which is statistically significant (P<0.05). .Conclusion: The modern information management mode is effective in regulation of checking and dispensing traditional Chinese medicine, and in the signicant reduction of error rate. At the same time, the medical staff are relatively qualified and standardized, and pharmacy staff must enhance their professional skills to reduce the prescription errors to a minimum.