| 引用本文:苏冬梅1，李树斌1，李军祥2，李影华1.基于健脾疏肝法观察超声药物透入治疗非酒精性脂肪性肝病30例[J].世界中医药,2017,(06):. |
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| 基于健脾疏肝法观察超声药物透入治疗非酒精性脂肪性肝病30例 |
| Observation of 30 Cases of Non-alcoholic Fatty Liver Disease Treated by Ultrasound Drug Penetration |
| 投稿时间：2016-11-06 |
| DOI：10.3969/j.issn.1673-7202.2017.06.039 |
| 中文关键词: 超声药物透入 健脾疏肝法 非酒精性脂肪性肝病 |
| English Keywords:Ultrasound drug penetration Spleen-tonifying and liver-soothing method Non-alcoholic fatty liver disease |
| 基金项目:北京市大兴区科技发展计划项目（编号：15048-1）——基于健脾疏肝法探讨超声离子透入对脂肪肝的疗效 |
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| 中文摘要: |
| 目的：观察健脾疏肝方采用超声药物透入治疗非酒精性脂肪性肝病（Non-alcoholic Fatty Liver Disease，NAFLD）的疗效。方法：选取2015年1月至2016年9月中国中医科学院广安门医院南区门诊及住院收治的NAFLD30例，随机分成2组，治疗组采用健脾疏肝方超声药物透入，对照组单纯采用超声离子透入，疗程3个月，随访3个月。观察患者体重指数、血清转氨酶（ALT、AST）、肝/脾CT值变化以及临床症状的改善。结果：无论单纯超声离子透入或者配合中药进行超声药物透入治疗均可有效改善NAFLD患者血清ALT、AST水平，降低患者肝/脾CT值，减轻患者脂肪肝程度，差异有统计学意义（P<0.001）；并可有效改善患者体重指数，差异有统计学意义（P<0.001），缓解患者肝区疼痛、脘腹胀满、乏力等临床症状。结论：本方采用超声药物透入外治NAFLD有较好疗效，其远期疗效体现饮食、运动等综合治疗在NAFLD治疗中的重要性。 |
| English Summary: |
| To observe the efficacy of ultrasound drug penetration in the treatment of NAFLD. Methods:A total of 30 patients were randomly divided into two groups. The treatment group were treated by ultrasound drug penetration of spleen-tonifying and liver-soothing medicine and the control group by ultrasound ion penetration. The treatment lasted for three months. Then, three-months’ follow-ups were performed for each patient. The monitored indexes included BMI, serum transaminase, liver/spleen CT ratio and clinical symptoms. Results:Both treatments in the two groups effectively improved the serum ALT, AST levels, reduced the patient’s liver/spleen CT value, improved the patient’s BMI, and relieved the clinical symptoms including liver pain, abdominal distention, and fatigue （P<0.001）. Conclusion:The formula in the treatment of NAFLD has a good effect with the long-term efficacy reflected in diet and sports. |
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