To observe patients with diabetes complicated with late-onset hypogonadism (LOH) reproductive hormone level and ADAM score in elderly male patients, and to explore the relationship based on the kidney storing the essence of different syndromes and reproductive hormone levels and ADAM scores. Methods:A total of 200 elderly male patients with LOH with type 2 diabetes were included and divided into four groups according to syndromes of kidney yin deficiency, kidney yang deficiency, kidney essence deficiency, and un-consolidation of the kidney-qi. All patients had tests on sex hormone and fasting blood glucose/fasting islet function, and the ADAM psychological scale was used for assessment. Results:Pituitary-hypothalamic system hormone of patients of the kidney yang deficiency and un-consolidation of the kidney-qi syndrome increased greatly and significantly higher in the LH and FSH, and estradiol increased significantly. The total testosterone levels, kidney yin deficiency type than the other three types did not decrease significantly. In ADAM score, reduction of physical symptoms and sexual function symptoms of kidney yang deficiency and un-consolidation of the kidney-qi was significant. Vasomotor symptoms of kidney yin deficiency were obvious. Psychological symptoms in kidney yang deficiency were significant. Conclusion:Hormone level and ADAM score in different TCM syndromes of elderly male patients with diabetic LOH have different performance, indicating the correlation between TCM syndromes and hormone levels and the score of ADAM.