世界中医药

目的:观察调心理气法治疗绝经综合征的临床疗效。方法:将120例绝经综合征患者随机分为3组,观察组40例、中药对照组40例、西药对照组40例;观察组采用调心理气法治疗,中药对照组采用六味地黄丸或右归丸治疗,西药对照组采用替勃龙治疗,3组疗程均为3个月。治疗前后测定Kupperman评分、血清雌二醇(E2)、卵泡生成素(FSH)水平。结果:3组治疗后Kupperman评分均较治疗前明显降低(P<0.05);调心理气法对患者Kupperman评分的改善情况明显优于传统中医补肾对照组(P<0.05),且疗效与西医激素对照组相当(P>0.05)。3组治疗前后FSH水平均未见明显统计学差异(P>0.05);血清E2水平西药对照组治疗后较治疗前明显上升(P<0.05),而中药观察组和中药对照组在治疗前后差异无统计学意义(P>0.05)。中药组观察组和西药对照组总有效率均为100%,明显高于中药对照组75%(P<0.05)。结论:调心理气法对绝经综合征患者的Kupperman评分有明显的改善作用,对FSH、E2无明显影响。

English Summary:

To observe the clinical effect of therapy of regulating metal activities and qi on menopause syndrome (MPS). Methods:A total of 120 patients meeting the diagnostic criteria were divided into three groups. The Chinese medicine treatment group (40 patients) was given therapy of regulating metal activities and qi. The Chinese medicine control group (40 patients) was given Zhibai Dihuang Pill or Yougui Pill. The control group (40 patients) was given with Tibolone Tablets. Patients in the three groups were treated for three months. The improvement of the kupperman score and the variation of their FSH and E2 in the blood serum were compared. Results:The kupperman score of the three groups all decreased after the treatment (P<0. 05). The kupperman score of the treatment group was superior to the Chinese medicine control group with the similar effect to that of the control group (P>0. 05), significantly better than the Chinese medicine control group (P<0. 05). There was no significant difference in FSH between the comparison before and after treatment in the three groups (P>0. 05). Serum E2 of the control group was significantly increased (P<0. 01). The total effective rate was 100% in the Chinese medicine treatment group and the control group, significantly better than the Chinese medicine control group (P<0.05). Conclusion:Therapy of regulating metal activities and qi can obviously improve the kupperman score of the patients with MPS, but have no effect on the Serum E2 and FSH.

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