To observe the effect of Qi-replenishing Yang-warming blood-activating circulation and Collaterals-dredging on angina pectoris after PCI for patients who were 80 years old or above.Methods:A total of 68 cases of elderly people over the age of 80 after PCI in patients with angina pectoris were randomly divided into treatment group and control group, the control group was given conventional western medicine treatment, and the treatment group added Qi-replenishing Yang-warming Blood-activating and Collaterals-dredging medicine on the basis of conventional western medicine, The treatment lasted for 8 weeks, then the 2 groups were observed and angina pectoris seizure frequency, duration of angina pectoris, 6 min walk test and left ventricular ejection fraction (LVEF%) were compared with before the treatment. In addition, the adverse reactions of patients after taking Qi-replenishing Yang-warming Blood-activating and Collaterals-dredging drug were recorded. Results:The condition of treatment group was significantly better than control group after 8 weeks' treatment(P<0.01). Seizure frequency as well as duration was less than the control group (P<0.01), 6 min walking test and improved left ventricular ejection fraction in treattment group were significantly better than that of control group (P<0.05). And there was not obvious adverse reactions of liver or kidney function. Conclusion:Supplementing Qi, warming Yang, activating blood circulation and dredging collaterals therapy can effectively relieve the occurrence of angina pectoris after PCI and improve the cardiac function of the elderly over 80 years old.