| To study the efficacy of Qishen Yiqi Dripping Pill combined with trimetazidine on the treatment of chronic heart failure of coronary heart disease and its effect on myocardium and blood lipid.Methods:A total of 94 patients with chronic heart failure due to coronary heart disease were randomly divided into observation group and control group with 47 cases in each group. The control group was given trimetazidine, while the observation group was additionally given Qishen Yiqi Dripping Pills, lasting for 8 weeks as the treatment of course. the therapeutic effect and changes in cardiac function, BNP, myocardial enzyme index, blood lipid index and adverse reaction of the two groups before and after the treatment were compared.Results:The total efficiency of the observation group (93.62%) was higher than that of the control group (74.47%) (P<0.05). LVEF of both the two group increased after the treatment, while LVEDD, LVESD, BNP, CK, CK-MB, TG, LDL-C and TC decreased after the treatment (P<0.05); LVEF of the observation group increased after the treatment, while LVEDD, LVESD, BNP, CK, CK-MB, TG, LDL-C and TC lower than those of the control group after the treatment (P<0.05). There was no severe adverse reaction in the two groups.Conclusion:Qishen Yiqi pill combined with trimetazidine Sibutramine in treating chronic heart failure due to coronary heart disease, safe and reliable, has obvious curative effect and can improve the myocardial enzymes and blood lipid in patients with no serious adverse reaction. |
