世界中医药

作者	单位
郭海明1,2，郭来旺1，邢建月3	1 山西晋康风湿病医院，太原，030000； 2 山西中医学院附属医院，太原，030024； 3 山西省中医药研究院，太原，030000

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中文摘要:

目的：观察蚂蚁通痹胶囊治疗类风湿关节炎的临床疗效。方法：选取2010年8月至2015年8月山西晋康风湿病医院收治的类风湿关节炎患者640例。随机分为观察组340例，对照组300例，观察2组患者疾病疗效及中医证候疗效、临床症状改善情况、随访12周DAS28变化情况。结果：2组患者疾病疗效较治疗前有明显改善，差异有统计学意义(P<0.05)；治疗后，在降低ESR、CRP、RF以及改善晨僵时间、关节肿胀数、握力和中医证候积分方面观察组优于对照组，差异有统计学意义(P<0.05)，且随访12周，病情基本平稳，观察组原服用的双氯芬酸钠肠溶胶囊（戴芬）已逐步减停。结论：蚂蚁通痹胶囊能有效治愈和改善类风湿关节炎患者的症状。

English Summary:

To observe the clinical efficacy of Mayi Tongbi capsule on thetreatment of rheumatoid arthritis. Methods:The patients with rheumatoid arthritis meeting the diagnostic criteria were randomly divided into the treatment group (340 cases), receiving Methotrexate combined with Diclofenac Sodium Enteric Capsules, and thecontrol group(300 cases), treated with Mayi Tongbi capsule combined with Diclofenac Sodium Enteric Capsules. Observation was made on the efficacy of the disease, the TCM syndrome, improvement of clinical symptoms, and the changes in DAS28 over 12 weeks of follow-up. Results:There was obvious improvement on the disease after treatment in the two groups, the difference being statistically significant (P<0.05); after treatment, the treatment shows better effect compared with in terms of decreasing ESR, CRP, RF and improving morning stiffness time, number of swollen joints, grip strength and TCM syndrome integral treatment group.There was statistic significance in the difference (P<0.05), and, the disease condition was relatively stable over 12-week follow up, with Diclofenac Sodium Enteric Capsules taken in the treatment group being gradually reeduced. Conclusion:The combination of Mayi Tongbi capsule and Diclofenac Sodium Enteric Capsules can effectively improve and cure the symptoms of rheumatoid arthritis patients.

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