世界中医药

目的：探讨针灸结合中药治疗周围性面神经麻痹的临床治疗效果及对患者免疫球蛋白的影响。方法：选取2014年10月至2016年10月西安市高陵区中医医院收治的周围性面神经麻痹患者110例，根据治疗方法不同分为针灸组和针药组，每组52，针灸组仅给予针灸疗法，针药组同时给予针灸和中药治疗。比较治疗后2组临床疗效，比较治疗前后不同时间2组患者面神经功能及免疫球蛋白IgA、IgG、IgM水平。结果：治疗后针药组临床总有效率高达96.15%，明显高于针灸组的81.03%，2组间差异有统计学意义（P<0.01）。针灸组治疗后2~4周H-B评分明显高于治疗前，针药组治疗后1~4周H-B评分明显高于治疗前，差异有统计学意义（P<0.05或P<0.01），且明显高于针灸组，差异有统计学意义（P<0.05或P<0.01）。治疗后2组患者血清IgA、IgG及IgM水平均明显降低，差异有统计学意义（P<0.01），且针药组明显低于针灸组，差异有统计学意义（P<0.05或P<0.01）。结论：针灸结合中药可迅速缓解周围性面神经麻痹患者临床症状和体征，改善患者面部神经功能，降低血清免疫球蛋白水平，提高整体治疗效果。

English Summary:

To study the clinical efficacy of acupuncture combined with Chinese medicinal on peripheral facial paralysis and its effect on immunoglobulin.Methods:A total of 110 cases of peripheral facial paralysis treated in the hospital from Oct. 2014 to Oct. 2016 were selected and divided into acupuncture group (n＝58) and acupuncture-medicine group (n＝52) according to different treatment methods. Acupuncture group was only given by acupuncture therapy, while acupuncture-medicine group was given by acupuncture and Chinese medicinal at the same time. The clinical effect after the treatment, facial nerve function and the levels of immunoglobulin IgA, IgG and IgM before and after the treatment were compared between the two groups.Results:The total effective rate was 96.15% in acupuncture-medicine group, which was significantly higher than 81.03% in acupuncture group, showing that the difference between the two groups had statistically significant (P<0.01). The House-Brackmann (H-B) score from two to four weeks after the treatment of the acupuncture group was significantly higher than that before the treatment, while it was significantly higher from 1 to 4 weeks after the treatment in the acupuncture-medicine group (P<0.05 orP<0.01), and significantly higher than those of the acupuncture group, showing statistically significant difference (P<0.05 orP<0.01). The levels of serum IgA, IgG and IgM in the two groups significantly decreased (P<0.01), and the acupuncture-medicine group was significantly lower than those in the acupuncture group, which showed that there was statistically significant difference (P<0.05 orP<0.01).Conclusion:Acupuncture combined with Chinese Medicinal may rapidly relieve clinical symptoms and signs of patients with peripheral facial paralysis, improve facial nerve function, reduce the level of immunoglobulin and improve the overall therapeutic effect.

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