| 引用本文:董青军1，李锋1，姚一博1，梁宏涛1，王琛1，郭修田2，曹永清1，陆金根1.理气活血化瘀通络中药治疗功能性便秘的疗效和安全性[J].世界中医药,2017,(08):. |
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| 理气活血化瘀通络中药治疗功能性便秘的疗效和安全性 |
| Efficacy and Safety Evaluation of Regulating qi and Activating Blood Formula in Treating Functional Constipation |
| 投稿时间：2017-01-05 |
| DOI：10.3969/j.issn.1673-7202.2017.08.046 |
| 中文关键词: 理气活血化瘀通络 功能性便秘 系统评价 |
| English Keywords:Regulating qi and Activating blood Functional constipation Systematic review |
| 基金项目:国家自然科学基金（81503577）;上海市卫生和计划生育委员会中医药科研基金项目（2014LP087A）;上海市浦东新区卫生局联合攻关项目（PW2013D-10）;上海市市级医院适宜技术项目（SHDC12014201）;上海中医药大学后备业务专家 |
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| 中文摘要: |
| 目的:评价理气活血化瘀通络中药治疗功能性便秘的有效性和安全性。方法:检索2010年1月至2014年12月中国期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、中国科技期刊全文数据库(VIP)，PUBMED等中英文数据库中理气活血化瘀通络中药治疗功能性便秘的随机对照临床研究，将痊愈率、总有效率、复发率、不良反应等作为结局指标，运用Revman 5.10软件评价分析。结果:共纳入18个随机对照临床试验，总样本量1 711例。理气活血化瘀通络中药治疗功能性便秘的痊愈率、总有效率、复发率等疗效性指标优于对照组（P<0.05），不良反应发生率低于对照组（P<0.05）。结论:理气活血化瘀通络中药治疗功能性便秘具有临床疗效好、复发率低、不良反应较少的特点。 |
| English Summary: |
| To observe the clinic effect of regulating qi and activating blood formula in treating functional constipation and evaluate its efficacy and safety basing on systematic review.Methods:Researchers searched randomized controlled trials related to regulating qi and activating blood herbal decoction in the treatment of functional constipation in Chinese and English databases during January 2010 to December 2014.Choosing cure rate,effective rate,recurrence rate and adverse reaction as final indicators.To evaluate efficacy and safety by Revman 5.10 software.Results:Eighteen RCTs and 1 711 patients were included in this systematic review.Meta analysis shows there are significant differences in cure rate,effective rate,recurrence rate and adverse reactions between treatment group and control group (P<0.05).Also,adverse reaction rate was significantly lower in the treatment group (P<0.05).Conclusion:Using regulating qi and activating blood herbal formula to treat functional constipation has significant efficacy and safety,with lower recurrence rate. |
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