| To study the curative effect of severe acute pancreatitis supplemented with Qingyi Decoction and its influence on systemic inflammatory response syndrome and key organs' function.Methods:A total of 58 severe acute pancreatitis patients in our hospital during June 2013 to August 2016 were included in our study,and they were divided into control group (30 cases),which received conventional western medicine treatment,and observation group (28 cases) which was treated Qingyi Decoction combined with western medicine therapy.The clinical symptom score,serum inflammatory mediators,liver and kidney function indexes in two groups were compared before and after treatment.Results:Before treatment,there were no significant differences between two groups in clinical symptom score,serum inflammatory mediators,liver function and renal function indexes (P>0.05).After treatment,the symptoms of abdominal pain,fullness,nausea and vomiting,dry mouth and dry thirst scores in observation group were lower than those in control group,serum contents of inflammatory mediators such as PCT,MCP-1,CRP,HMGB-1 were lower than those in control group,liver function indexes such as AST,ALT,TBIL were lower than those in control group,renal function indexes such as Scr,BUN were lower than those in control group.Conclusion:Qingyi Decoction therapy can significantly reduce the clinical symptoms of patients with severe acute pancreatitis,decrease systemic inflammatory response,and protect liver and kidney function. |
