| 引用本文:凌望，张蕾，程大雁，朱锦星，周苗，董耀荣，吴美平.从cTnI探讨强心方对慢性心力衰竭患者心肌保护作用[J].世界中医药,2017,(09):. |
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| 从cTnI探讨强心方对慢性心力衰竭患者心肌保护作用 |
| Discussion on the Protective Effect of Qiangxin Fang on Myocardiumof Patients with Chronic Heart Failure from cTnl |
| 投稿时间：2017-06-17 |
| DOI：10.3969/j.issn.1673-7202.2017.09.025 |
| 中文关键词: 强心方 慢性心力衰竭 心肌肌钙蛋白I N末端脑钠肽前体 |
| English Keywords:Qiangxin Fang Chronic heart failure Cardiac troponin l N-terminal pro-brain natriuretic peptide |
| 基金项目:国家自然科学基金项目(81473379,81673915);上海市自然科学基金项目(16ZR1434500) |
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| 中文摘要: |
| 目的:观察强心方在治疗慢性心力衰竭患者对其心肌肌钙蛋白I(cTnI)及N末端脑钠肽前体(NT-proBNP)水平的影响,基于cTnI水平的变化,探讨强心方对心肌损伤的保护作用。方法：选取2016年3月至2017年3月上海中医药大学附属上海市中医医院门诊和住院收治的慢性心力衰竭患者120例,随机分为观察组和对照组,每组60例。其中,观察组采用强心方联合常规西医治疗方法;而对照组仅使用常规西医方法,治疗时间均为8周。结果：治疗后,观察组与对照组cTnI和NT-proBNP水平均有显著降低(P<0.05),且与对照组比较,观察组cTnI和NT-proBNP水平显著降低(P<0.05)。结论：强心方联合常规西医治疗方法对慢性心力衰竭患者cTnI和NT-proBNP指标均有改善作用,且强心方对慢性心力衰竭患者的心肌损伤有保护作用。 |
| English Summary: |
| To observe the effect of Qiangxin Fang on levels of cardiac troponin l (cTnl) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in the treatment to patient with chronic heart failure, and also to explore the protective effect of Qiangxin Fang on myocardial injury based on the changes of cTnl level.Methods:A total of 120 patients with chronic heart failure who were treated in outpatient and hospitalized in Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine from March 2016 to March 2017, were randomly divided into treatment group and control group, with 60 cases in each.The treatment group was treated with Qiangxin Fang combined with conventional western medicine treatment methods, while the control group was not received conventional western medicine treatment.Both groups were treated for 8 weeks.Results:After treatment, the levels of cTnl and NT-proBNP in two groups were significantly decreased (P<0.05).And the levels of cTnl and NT-proBNP in treatment group were significantly decreased compared with control group (P<0.05).Conclusion:Qiangxin Fang combined with conventional western medicine treatment has improvement effect on levels of cTnl and NT-proBNP for patients with chronic heart failure, and Qiangxin Fang has protective effect on myocardial injury of patients with chronic heart failure. |
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