世界中医药
文章摘要
引用本文:王成龙1,2,赵东峰1,杨志烈1,3,贾友冀1,4,常君丽1,王拥军1,杨燕萍1.环磷酰胺诱导的小鼠骨髓抑制模型及中药对其防治作用机制研究进展[J].世界中医药,2017,(09):.  
环磷酰胺诱导的小鼠骨髓抑制模型及中药对其防治作用机制研究进展
Mouse Model of Cyclophosphamide-Induced Myelosuppression and Research Progress on Mechanism of Action of Chinese Meteria Medica in its treatment and prevention
投稿时间:2016-10-19  
DOI:10.3969/j.issn.1673-7202.2017.09.064
中文关键词:  环磷酰胺  化疗  骨髓抑制  小鼠模型  机制研究
English Keywords:Cyclophosphamide  Chemotherapy  Myelosuppression  Mouse model  Study of Mechanism
基金项目:国家自然科学基金项目(81202708,81373667,81674006)
作者单位
王成龙1,2,赵东峰1,杨志烈1,3,贾友冀1,4,常君丽1,王拥军1,杨燕萍1 1 上海中医药大学附属龙华医院脊柱病研究所,上海,200032
2 上海中医药大学附属龙华医院科技中心实验室,上海,200032
3 滨州医学院中西医结合学院,烟台,264003
4 上海交通大学医学院附属瑞金医院骨科,上海,200025 
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中文摘要:
      化疗后骨髓抑制容易导致患者发生感染或出血,严重影响患者治疗、预后和生命质量,甚至危及生命,给患者及家属带来很大痛苦。中医药防治化疗导致骨髓抑制越来越受到重视。随着骨髓抑制动物模型的建立、应用和成熟,中药防治化疗导致骨髓抑制机制的研究也取得许多进展,显出中药治疗的优势和前景。
English Summary:
      Patients with chemotherapy-induced myelosuppression is prone to infection or bleeding,which has a serious impact on their treatment,prognosis and quality of life and even endangers life and leads patients and their family to suffering.In recent years,traditional Chinese medicine in preventing and treating chemotherapy-induced myelosuppression have gradually garnered increasing attention.As the animal model of myelosuppression is being established,applied and mature,research on mechanism of Chinese meteria medica in preventing and treating chemotherapy-induced myelosuppression has made great achievements,showing the advantages and prospect of Chinese meteria medica in the treatment of this disease.
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