To observe the clinical curative effect of Buzhongyiqi granules in the treatment of allergic rhinitis with deficiency of spleen qi. Methods:A total of 60 outpatients with allergic rhinitis were divided into an observation group and a control group randomly, 30 cases in each group. The control group was treated with Ebastine oral treatment, the observation group Buzhong Yiqi granule. Symptoms score and clinical efficacy were observed. Results:The symptom score of the two groups before and after treatment had significant changes (P<0.05); symptom score before and after treatment between the groups compared in terms of runny nose, stuffy nose, and runny or itchy nose integral showed no differences (P>0.05), but in terms of the integral of sneezing the observed group was better than that of the control group (P<0.05). The clinical efficacy of the two groups was compared, and the total effective rate of observation group was 80%, the control group 83.3%, with no statistical difference between the two groups (P<0.05).Conclusion:Buzhongyiqi granules in oral treatment on allergic rhinitis with deficiency of Spleen Qi is one of the effective methods, especially in improving sneezing, has more advantages and is worthy of clinical application.