To explore the application effect of self-made Chinese medicine fumigation group in Milligan-Morgan of mixed hemorrhoids.Methods:A total of 120 patients who were received Milligan-Morgan of mixed hemorrhoids in our hospital from July 2015 to July 2017 were selected as the subjects and divided into the control group and treatment group according to random number table，with 60 cases in each group.The control group was treated with potassium permanganate 1：5 000 bath，and the treatment group was treated with self-made Chinese medicine fumigation group.The degree of pain，the degree of edema and the time of wound healing and the length of hospital stay were compared at 3，5 and 7 days after operation，and the clinical efficacy of the two groups was evaluated.Results:At 3，5 and 7 days after operation，the pain score and edema score of the treatment group were significantly lower than those of the control group，and the difference was statistically significant (P<0.05).The healing time (12.65±2.42)d and hospitalization time (6.78±1.91)d of the treatment group were significantly shorter than the control group (20.57±2.63)d and (13.57±2.45)d，and the difference was statistically significant (P<0.05); The total effective rate was 93.33% (56/60，56/60) in the treatment group，which was significantly higher than that in the control group (76.67%，46/60)，and the difference was statistically significant (P<0.05).Conclusion:Self-made Chinese medicine fumigation group in post-operation of Milligan-Morgan of mixed hemorrhoids can significantly improve clinical efficacy，reduce the degree of edema，shorten the wound healing time，hospital stay，reduce the pain of patients to promote the recovery of patients with significant advantages and higher clinical significance.