世界中医药
文章摘要
引用本文:沈艳,唐红,周端.2型糖尿病患者中医体质类型分布特点及与相关危险因素的关系研究[J].世界中医药,2017,(10):.  
2型糖尿病患者中医体质类型分布特点及与相关危险因素的关系研究
Research on Distribution Characteristics of TCM Constitution of Patients with Type 2 Diabetes Mellitus and Related Risk Factors
投稿时间:2016-06-15  
DOI:10.3969/j.issn.1673-7202.2017.10.053
中文关键词:  2型糖尿病  中医体质  相关指标
English Keywords:Type 2 diabetes mellitus  TCM constitution  Index correlation
基金项目:国家中医药管理局中医药行业专项(201007003);龙华医院院级科研基金项目(2014YM03)
作者单位
沈艳,唐红,周端 上海中医药大学附属龙华医院上海200032 
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中文摘要:
      目的:通过对2型糖尿病患者进行中医体质类型的辨识,调查分析2型糖尿病患者中医体质类型分布特点,探索2型糖尿病患者常见体质类型,并对其与相关危险因素的关系进行初步研究,为建立2型糖尿病发病的中医病因学理论提供科学依据,也为临床防治提供依据。方法:选取2014年6月至2015年12月来自4家社区卫生服务中心的门诊或体检患者947例,其中2型糖尿病患者461例,非糖尿病对照组人群486例,参照中华中医药学会《中医体质分类判定》标准进行中医体质辨识,并记录糖尿病患者的性别、年龄、身高、体重、BMI、吸烟史、饮酒史、高血压病史、心脑血管疾病史、血脂异常病史等,进行统计学分析。结果:2型糖尿病患者9种体质按分布频率由高到底依次为:阴虚质、痰湿质、血瘀质、气虚质、阳虚质、湿热质、平和质、气郁质、特禀质;2型观察组平和质所占比例低于非观察组,阴虚质所占比例高于非观察组,差异有统计学意义(P<0.01);logistic回归分析筛选出阴虚质为2型糖尿病的主要危险体质,差异有统计学意义(P<0.01,OR=1.887)。平和质为2型糖尿病的主要保护体质,差异有统计学意义(P<0.01,OR=0.239)。2型糖尿病人群中主要体质人群中不同性别、年龄、体重指数、高血压病史、冠心病、脑梗及血脂异常患病率比较,差异有统计学意义(P<0.01~0.05)。结论:阴虚质为2型糖尿病的主要危险体质,平和质为其主要保护体质,为其防治提供了理论依据;2型糖尿病各主要体质间心脑血管危险因素发生率表现各异,因此预后可能不同,应全面关注其各项指标及相关疾病患病率,制定个性化防治方案。
English Summary:
      To analyze distribution characteristics of TCM constitution of patients with type 2 diabetes mellitus and to explore common constitutional types through the investigation of TCM constitution in type 2 diabetes mellitus patients.To study preliminarily the relationship between the TCM constitution and the related risk factors in order to provide scientific basis for the establishment of the pathogenesis of type 2 diabetes mellitus and the basis for clinical prevention and treatment.Methods:A total of 461 patients with type 2 diabetes mellitus who were admitted and treated in Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from June 2014 to December 2015 were selected and 486 healthy people as control group.A total of 947 cases were studied.According to TCM Constitution Classification Standard of China Association of Chinese Medicine,the cases were identified and the patients were analyzed in gender,age,height,weight,BMI,history of smoking and drinking,hypertension history,cardiovascular disease history,dyslipidemia disease history and so on.Results:The distribution frequency of nine kinds of TCM constitutions in the patients with type 2 diabetes mellitus from high to low was yin-deficiency constitution,phlegm-dampness constitution,blood stasis constitution,qi-deficiency constitution,yang-deficiency constitution,dampness-heat constitution,mild constitution,qi stagnation constitution and specific constitution.The proportion of mild constitution in the patients with type 2 diabetes mellitus was lower than control group,and yin-deficiency constitution was higher (P<0.01).Logistic regression analysis screened out that yin-deficiency constitution had highest risk for the patients with type 2 diabetes mellitus (P<0.01,OR=1.887),and mild constitution had second risk (P<0.01,OR=0.239).The difference of patients of yin-deficiency constitution with type 2 diabetes mellitus in the gender,age,weight,hypertension history,cardiovascular disease history and prevalence of dyslipidemia had statistical significance (P<0.01~0.05).Conclusion:The yin-deficiency constitution is main risk constitution and mild constitution is protection constitution for the patients with type 2 diabetes mellitus.It provides a theoretical basis for its prevention and treatment.The cardiovascular disease risk factors among the main constitutions of type 2 diabetes mellitus are different,so there may have different prognosis.We should pay attention to each index and the prevalence of related diseases to develop personalized treatment scheme.
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