| 引用本文:牟世祥，李海永，王文瑞，杨寿涛，李明明.活血利水组方联合器械光动力疗法预防下肢骨折术后深静脉血栓的临床效果[J].世界中医药,2017,(11):. |
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| 活血利水组方联合器械光动力疗法预防下肢骨折术后深静脉血栓的临床效果 |
| Clinical Study on Invigorating Blood and Draining Water Formula Combined with Instrumental Photodynamic Therapy in Preventing Lower Extremities Fracture Postoperative Deep Venous Thrombosis |
| 投稿时间：2015-09-27 |
| DOI：10.3969/j.issn.1673-7202.2017.11.014 |
| 中文关键词: 活血利水组方 光动力疗法 深静脉血栓 |
| English Keywords:Invigorating blood and draining water formula Photodynamic therapy DVT |
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| 中文摘要: |
| 目的：探讨活血利水组方联合器械光动力疗法预防下肢骨折术后深静脉血栓（Deep Venous Thrombosis，DVT）的临床疗效。方法：选取2014年2月至2015年1月接受下肢骨折手术的患者86例，依据随机数表法分为观察组（43例）和对照组（43例）。对照组给予活血利水组方治疗，观察组在对照组的基础上进行器械光动力疗法。比较2组患者的凝血、纤溶指标（纤维蛋白原、D-二聚体、凝血酶原时间及活化部分凝血酶原时间）及血液流变学指标（全血黏度、红细胞比容及血浆黏度），并统计2组患者DVT阳性数据。结果：治疗前，2组患者的纤维蛋白原、D-二聚体、凝血酶原时间及活化部分凝血酶原时间的组间差异无统计学意义（P>0.05）。治疗后，观察组患者的纤维蛋白原、D-二聚体水平明显降低，凝血酶原时间及活化部分凝血酶原时间略有提高，除凝血酶原时间外，2组患者的凝血、纤溶指标差异有统计学意义（P<0.05）。治疗前，2组患者的全血黏度、红细胞比容及血浆黏度的组间差异无统计学意义（P>0.05）。治疗后，观察组患者的全血黏度、红细胞比容及血浆黏度均明显降低，与对照组比较，差异有统计学意义（P<0.05）。观察组出现3例（6.98%）DVT患者，对照组出现8例（18.60%）DVT患者，差异有统计学意义（P<0.05）。结论：活血利水组方联合器械光动力疗法在预防下肢骨折术后深静脉血栓方面具有明显优势。 |
| English Summary: |
| To explore the clinical effect of invigorating blood and draining water formula combined with instrumental photodynamic therapy in preventing lower extremities fracture postoperative deep venous thrombosis (DVT). Methods:A total of 86 patients who were received lower limbs fracture operation in our hospital from February 2014 to January 2015 were divided into observation group (43 cases) and control group (43 cases) according to the random digit table. The patients in control group were treated with invigorating blood and draining water formula, while the patients in conservation group were treated with instrumental photodynamic therapy on the basis of the control group. The coagulant and fibrinolytic index (Fibrinogen, D-dimer, prothrombinogen time and activated partial prothrombinogen time) as well as hemorheology index (blood viscosity, erythrocrit and plasma viscosity) of the both group patients were compared, and DVT positive data was collected. Results:Before the experiment, the difference was not statistically significant in fibrinogen, D-dimer, prothrombinogen time and activated partial prothrombinogen time between the two groups (P>0.05). After the experiment, the level of fibrinogen and D-dimer in the observation group was significantly decreased, while the prothrombinogen time and the activated partial prothrombinogen time were slightly increased. In addition to the prothrombinogen time, the coagulant and fibrinolytic index of the two groups were significantly different, with statistically significant (P<0.05). Before the experiment, the difference was not statistically significant in blood viscosity, erythrocrit and plasma viscosity between the two groups (P>0.05). After the experiment, the blood viscosity, hematocrit and plasma viscosity of the observation group were significantly decreased. Compared with those in the control group were significant different, with statistically significant (P<0.05). There were 3 cases (6.98%) of DVT patients in the observation group and 8 cases (18.60%) of DVT patients in the control group, with statistically significant difference (P<0.05). Conclusion:The invigorating blood and draining water formula combined with instrumental photodynamic therapy in preventing lower fracture postoperative deep venous thrombosis has significant advantages, worthy of clinical promotion. |
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