世界中医药

目的：探讨加味乌梅汤治疗失眠症的临床及超声特征。方法：选取济宁市中医院于2015年6月至2016年6月收治的失眠症患者60例，依据随机数字表法将60例失眠症患者分为观察组30例与对照组30例。观察组患者服用加味乌梅汤治疗，对照组患者口服艾司唑仑治疗。2组疗程均为14 d。比较2组治疗疗效，治疗前后PSQI评分、脑动脉超声影像学及主要症状积分变化及不良反应情况。结果：观察组临床疗效总有效率（93.33%）高于对照组（66.67%）（P<0.05）；观察组中医症状总有效率（96.67%）高于对照组（63.33%）（P<0.05）；观察组患者治疗后PSQI评分低于对照组（P<0.05）；观察组患者治疗后大脑中动脉、基底动脉及椎动脉的Vs、Vm高于对照组，而RI低于对照组（P<0.05）；观察组患者治疗后神疲倦怠、心悸易惊、晨起困倦、多梦易醒、入睡困难积分低于对照组（P<0.05）；2组均未发生明显不良反应。结论：加味乌梅汤治疗失眠症的临床疗效，可改善患者脑血流状况，具有重要研究意义。

English Summary:

To pursue the clinical and echocardiographic study of modified Wumei Decoction in the treatment of insomnia.Methods:Sixty cases of insomnia were divided into an observation group and a control group,each 30 cases.The observation group's patients took modified Wumei decoction,the control group estazolam.The course of the two groups were all 14 d.The therapeutic effect of the two groups,PSQI score,cerebral artery ultrasound imaging and the main symptom score changes before and after treatment were compared,as well as adverse reactions.Results:The total effective rate of the observation group (93.33%) was higher than that of the control group (66.67%) (P<0.05); TCM symptoms total effective rate of the observation group (96.67%) was higher than that of the control group (63.33%) (P<0.05); patients in the observation group after treatment had lower PSQI score (P<0.05); after treatment,middle cerebral artery,basilar artery and vertebral artery Vs,Vm of patients in the observation group were higher than those of the control group,while RI was lower (P<0.05); after treatment,patients' core of tiredness,palpitations,being easily surprised,sleepiness in the morning,over dreaming,being easy to wake up,sleep difficulties in the observation group were lower than those of the control group (P<0.05); the two groups showed no obvious adverse reactions.Conclusion:The modified Wumei decoction can improve the cerebral blood flow state of patients in the clinical treatment of insomnia and is worthy of study.

查看全文查看/发表评论下载PDF阅读器