To observe the effect of lung,spleen,kidney co-regulating therapy in the treatment of chronic gout patients.Methods:From March 2014 to December 2016,78 patients with chronic gout were collected,then divided into observation group and control group randomly,each with 39 cases.The control group was given basic treatment and oral administration of Allopurinol Tablets,while the observation group,on the basis of that,used lung and spleen and kidney co-regulating therapy.Symptoms after 2 weeks of treatment,symptom score,biochemical indexes (UA urea nitrogen BNU,uric acid,ESR and ESR rheumatoid factor RF),and adverse reactions were compared between the two groups.Results:The effective rate of the observation group was 51.28%,the total effective rate was 97.44%,which were significantly higher than those of the control group of 25.64% and 82.05%,so the difference is statistically significant (P<0.05).After treatment,two groups of joint pain and joint swelling,and joint flexion and extension adverse scores were significantly lower than before treatment,and the scores of the observation group were significantly lower than the control group (P<0.05).After treatment,the levels of UA,BUN,ESR and RF in the two groups were significantly lower than those before treatment,and the above biochemical indexes in the observation group were significantly lower than those in the control group(P<0.05).The total incidence of adverse reactions in the observation group was 7.69%,significantly lower than the control group of 25.64% (P<0.05).Conclusion:Lung,spleen and kidney co-regulating therapy can effectively treat chronic gout patients.The therapy is effective and worthy of promotion in clinical.