As the development of science,technology and the Internet,medical research has entered the era of big data.Under the background of information explosion,the traditional Chinese medicine research gradually shows some defects while it is more suitable for the study of the real world to be based on big data.This paper analyzed the correlation between big data and traditional Chinese medicine,combing the current status and limitations of traditional Chinese medicine clinical research.We proposed new a research idea (Big data Clinical Trail) which should be set up under the background of big data.In addition,we should make full use of data mining technique to explore the value of it in order to provide a certain feasibility and reference value for the research direction of Chinese medicine.