| 引用本文:温敏勇，杨柳柳，夏欣田.中药自拟方剂联合无创通气对老年慢性肺心病急性加重期患者的临床疗效[J].世界中医药,2017,(12):. |
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| 中药自拟方剂联合无创通气对老年慢性肺心病急性加重期患者的临床疗效 |
| Curative Effects of Self-made Traditional Chinese Medicine Prescription Combined with Conventional Treatment and Non-invasive Ventilation on Elderly Patients WITH Chronic Pulmonary Heart Disease at Acute Exacerbation |
| 投稿时间：2017-08-10 |
| DOI：10.3969/j.issn.1673-7202.2017.12.015 |
| 中文关键词: 慢性肺心病 急性加重期 无创通气 中药方剂 临床疗效 |
| English Keywords:Chronic pulmonary heart disease Acute exacerbation period Non-invasive ventilation Traditional Chinese medicine prescription Clinical curative effect |
| 基金项目:广东省省级科技计划项目(2014A020209074) |
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| 中文摘要: |
| 目的:探讨中医药联合无创通气对老年慢性肺心病急性加重期患者的临床疗效。方法:选取2014年1月至2016年12月我院收治的老年慢性肺心病加重期患者82例,按照随机数字表法,分为对照组和观察组,各41例。对照组患者的治疗方法为抗炎、吸氧、祛痰平喘,强心及无创通气治疗。观察组在对照组治疗基础上,联合自拟方剂(组方:炙麻黄10 g、北杏仁15 g、浙贝母15 g、紫苏子15 g、全瓜蒌30 g、桑白皮15 g、桃仁15 g、丹参15 g、茯苓15 g、车前子15 g、地龙15 g、益母草30 g、甘草6 g)进行治疗,比较2组临床治疗效果、动脉血气指标、肺动脉压和心输出量等指标。结果:治疗后,观察组临床治疗总有效率高于对照组;观察组主要症状、次要症状、体征积分及CAT积分下降程度较对照组显著;观察组PaO2水平、PEF和FEV1水平均高于对照组,PaCO2水平低于对照组;动脉平均压降低,心输出量增加,均明显优于对照组(P<0.05)。结论:中药自拟方剂联合常规治疗和无创通气治疗老年慢性肺心病患者急性加重期的临床疗效显著,可改善患者肺功能,降低肺动脉平均压,增加心输出量,值得在临床上推广应用。 |
| English Summary: |
| To explore the clinical effects of traditional Chinese medicine combined with non-invasive ventilation in patients with acute exacerbation of chronic pulmonary heart disease. Methods:A total of 82 cases of elderly chronic pulmonary heart disease who were treated in our hospital from January 2014 to December 2016 were selected and divided into control group and observation group according to the random number table method, with 41 cases in each group. The treatment methods of the control group were anti-inflammatory, oxygen-absorbing, anti-phlegm breathing, strong heart and non-invasive ventilation. The observation group was treated on the basis of the control group, combined with the treatment of pseudo formulae (prescription:Herba Ephedrae 10 g, Semen Armeniacae Amarum 15 g, Bulbus Fritillariae Thunbergii 15 g, Perillae Fructus 15 g, Fructus Trichosanthis 30 g, Cortex Mori 15 g, Semen Persicae 15 g, Radix Salviae Miltiorrhizae 15 g, Poria 15 g, Semen Plantaginis 15 g, Lumbricus 15 g, Herba Leonuri 30 g, Radix Glycyrrhizae 6 g). The clinical treatment effects, arterial blood gas index, pulmonary arterial pressure and cardiac output were compared. Results:After treatment, the total effective rate of observation group was higher than that of the control group. The primary symptoms, secondary symptoms, signs and CAT integrals of the observation group were significantly lower than that of the control group. The levels of PaO2, PEF and FEV1 of observation group were higher than those in the control group, and the level of PaCO2 was lower than that in the control group. The average pressure of the artery decreased, and the increase of cardiac output was better than that of the control group (P<0.05). Conclusion:The clinical curative effect of traditional Chinese medicine prescription combined with conventional treatment and non-invasive ventilation for the treatment of elderly patients with chronic pulmonary heart disease in acute exacerbation is remarkable and distinct, which can improve lung function of patients, reduce the average pulmonary artery pressure, increase cardiac output, and it is worthy of popularization and application in clinic. |
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