| 引用本文:滕婧1，2，余俊1，2，3，廖红玉1，2.补肾活络方联合达英-35治疗多囊卵巢综合征肾虚血瘀证的临床效果[J].世界中医药,2017,(12):. |
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| 补肾活络方联合达英-35治疗多囊卵巢综合征肾虚血瘀证的临床效果 |
| Clinical Research on Bushenhuoluo Decoction Combined with Diane-35 in the Treatment of Polycystic Ovarian Syndrome with Kidney Deficiency And Blood Stasis Syndrome |
| 投稿时间：2017-02-15 |
| DOI：10.3969/j.issn.1673-7202.2017.12.019 |
| 中文关键词: 多囊卵巢综合征 肾虚血瘀证 补肾活络方 达英-35 中西医结合 |
| English Keywords:Polycystic ovarian syndrome Kidney deficiency and blood stasis syndrome Bushen Huoluo decoction Diane-35 Traditional Chinese and western medicine therapy |
| 基金项目:湖北中医药大学青苗资助项目(2016zzx010） |
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| 中文摘要: |
| 目的：观察补肾活络方联合达英-35治疗多囊卵巢综合征（Polycystic Ovarian Syndrome，PCOS）肾虚血瘀证的临床疗效。方法：将76例诊断符合PCOS肾虚血瘀证的患者，按照随机数表法分成观察组与对照组，每组38例。观察组给予补肾活络方联合达英-35口服治疗，对照组给予达英-35口服治疗，共治疗3个周期，观察治疗前、治疗3个周期后，停药后第3个周期患者血清睾酮(T)、卵泡刺激素(Follicle-stimulating Hormone，FSH)、黄体生成素(Luteinizing Hormone,LH)、LH/FSH水平与双侧卵巢平均卵巢体积（Mean Ovarian Volume，MOV）、平均卵泡数目（Mean F0llicle Number，MFN）等指标。结果：治疗3个周期后2组患者的性激素水平和超声检查指标均较治疗前明显改善，但停药后第3个周期，对照组各项指标又恢复到治疗前水平，而观察组仍保持治疗后水平。结论：补肾活络方联合达英-35治疗POCS肾虚血瘀证不仅近期疗效确切，且远期疗效优于单用达英-35。 |
| English Summary: |
| To observe the clinical effect of Bushen Huoluo decoction combined with Diane-35 in the treatment of polycystic ovarian syndrome with kidney deficiency and blood stasis syndrome.Methods:Seventy-eight patients diagnosed with polycystic ovarian syndrome were randomly divided into the treatment group and the control group.Those in the treatment group were treated by Bushen Huoluo decoction combined with Diane-35.Those in the control group were treated by Diane-35.Both groups were treated for 3 cycles.The serum sex hormones levels ［follicle-stimulating hormone (FSH),luteinizing hormone(LH),Testosterone(T),LH/FSH］ and the mean ovarian volume(MOV),mean follicle number(MFN)were compared between the two groups before treatment,after 3 cyclic treatment and at the 3th cycle after treatment.Results:The levels of relevant hormones and the indexes of B-ultrasonic were obviously improved after treatment in the two groups.However,3 cycles after treatment，these changes restored to the baseline as those before treatment in the control group,while maintained in the treatment group.Conclusion:Bushen Huoluo decoction combined with Diane-35 in treating polycystic ovarian syndrome not only shows marked short-term effect but also consolidate the curative effect.It is worth further research and promotion. |
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