世界中医药

目的：探讨中西医结合疗法对帕金森病患者睡眠障碍的疗效。方法：以入院病例号为编号，根据随机数字表，将120例帕金森睡眠障碍患者随机分成2组，每组60例。2组均给予帕金森西医常规疗法，对照组在常规疗法基础上给予佐匹克隆，7.5 mg，口服，每晚；观察组在常规治疗基础上给予补肾定颤安神方，2组患者均治疗21 d。治疗后，观察患者临床疗效、PSQI量表评分及不良反应发生情况。结果：2组患者组内治疗后PSQI量表评分均低于治疗前，P<0.05。观察组治疗后PSQI量表评分明显低于对照组治疗后，P<0.05。观察组治疗后临床总有效率（93.4%）明显高于对照组（63.3%），P<0.01。观察组各种不良反应发生率均低于对照组，P<0.01。结论：中西医结合疗法能后有效降低帕金森睡眠障碍患者PSQI量表评分，提高临床疗效，减少不良反应的发生率。

English Summary:

To explore the curative effect of integrated traditional Chinese and Western Medicine on sleep disorders in patients with Parkinson disease. Methods:According to the case number and the random number table, 120 patients with Parkinson sleep disorder were randomly divided into two groups, with 60 cases in each group. Two groups were given Parkinson conventional treatment of western medicine. The control group was treated with conventional therapy based on zopiclone 7.5 mg, oral administration, qn. The observation group on the basis of conventional treatment was given Bushen Dingchan Anshen Fang. The two groups were treated for 21 days. After treatment, the clinical efficacy, PSQI scale score and adverse reactions were observed. Results:The PSQI score of two groups after treatment was lower than that before treatment (P<0.05). After treatment, PSQI scores of the observation group were significantly lower than the control group after treatment (P<0.05). After treatment the total clinical efficiency (93.4%) in the observation group was significantly higher than the control group (63.3%) (P<0.01). All kinds of adverse reaction rate in the observation group was lower than the control group, (P<0.01). Conclusion:The combination of traditional Chinese medicine and Western medicine can effectively reduce the PSQI scale score of patients with Parkinson sleep disorder, improve the clinical efficacy and reduce the incidence of adverse reactions.

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