| 引用本文:赵智华，李科军，赵晓彬，马青敏，贾志旸.芪明颗粒联合人工泪液、非甾体消炎药滴眼液治疗对超声乳化手术术后干眼症患者损伤角膜上皮的作用[J].世界中医药,2017,(12):. |
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| 芪明颗粒联合人工泪液、非甾体消炎药滴眼液治疗对超声乳化手术术后干眼症患者损伤角膜上皮的作用 |
| Effects of Qiming Granule Combined with Artificial Tears, NSAIDs Eye Drops on Corneal Epithelial Injury Repair in Patients with Dry Eye after Phacoemulsification Surgery |
| 投稿时间：2017-02-22 |
| DOI：10.3969/j.issn.1673-7202.2017.12.027 |
| 中文关键词: 芪明颗粒；人工泪液；非甾体消炎药 滴眼液；干眼症；损伤角膜上皮 |
| English Keywords:Qiming granule Artificial tears NSAIDs eye drops Dry eye Corneal epithelial injury |
| 基金项目:河北省中医药管理局科研计划(2014154）——芪明颗粒治疗2型糖尿病患者内眼手术后干眼的临床观察 |
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| 中文摘要: |
| 目的：研究芪明颗粒联合人工泪液、非甾体消炎药滴眼液治疗在超声乳化手术术后修复干眼症患者损伤角膜上皮中的作用。方法：选取2014—2016年在超声乳化手术术后出现干眼症的患者202例（共计374眼），并按照随机分组法将202例在超声乳化手术术后出现干眼症的患者分为实验组101例（共计191眼）和对照组101例（共计183眼），其中包括实验组42例有角膜上皮损伤的干眼症患者和对照组39例有角膜上皮损伤的干眼症患者。对照组所有干眼症患者均常规使用人工泪液以及非甾体消炎药滴眼液进行治疗，剂量和频次均严格按照说明书规定使用，使用时间为1个月；实验组所有干眼症患者重复对照组以上所有治疗操作且严格按照服用规格要求使用芪明颗粒联合治疗，使用时间为1个月，比较2组的治疗效果（包括泪液分泌试验Schirmer值、泪膜破裂时间、对修复损伤角膜上皮的疗效）。结果：经过1个月的治疗后，对照组的泪膜破裂时间以及泪液分泌试验Schirmer值都显著低于实验组的泪膜破裂时间以及泪液分泌试验Schirmer值（P<0.05）；实验组干眼症患者的损伤角膜上皮的修复程度和效果优于对照组干眼症患者，且其治愈率也远远高于对照组干眼症患者（P<0.05）。结论：芪明颗粒联合人工泪液、非甾体消炎药滴眼液在治疗超声乳化手术术后出现干眼症伴角膜上皮损伤的患者有显著的临床疗效。 |
| English Summary: |
| To study the effects of Qiming granule combined with artificial tears, NSAIDs eye drops in the treatment of corneal epithelial injury repair in patients with dry eye after phacoemulsification.Methods:A total of 202 patients diagnosed as dry eyes (374 eyes) after phacoemulsification surgery were selected in our hospital during 2014 to 2016, and randomly divided into experimental group with 101 cases (191 eyes) and control group with 101 cases (183 eyes), including 42 dry eye cases with corneal epithelium injury in the experimental group and 39 dry eye cases with corneal epithelial injury in the control group.The control group was treated with artificial tears and NSAIDs eye drops, whose dose and frequency were strictly in accordance with the specification for 1 month.On the basis of that, the experimental group was treated with Qiming granule for 1 month.The treatment effects of 2 groups (including tear secretion test Schirmer value, tear break-up time, curative effects on repairing the damage of corneal epithelium) were compared.Results:After 1 months of treatment, the break-up time and tear secretion test Schirmer values of the control group were significantly lower than the experimental group (P<0.05); the repair degree and effects of corneal epithelial injury in the experimental group was much better than the control group, and the cure rate was far higher than that of the control group (P<0.05).Conclusion:Qiming granule combined with artificial tears and NSAIDs eye drops in the treatment of dry eye patients with corneal epithelial injury after phacoemulsification surgery has significant clinical efficacy. |
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