世界中医药

目的：探究针刺风池穴对高血压病的临床疗效及对TNF-α的调节作用。方法:选取2013年8月至2015年8月我院针灸科住院治疗并诊断为原发性高血压的患者600例,随机分为对照组和观察组,各300例。对照组给予苯磺酸氨氯地平片治疗;观察组在此基础上予针刺风池穴治疗;7 d为1个疗程,共治疗2个疗程。治疗后比较2组治疗前后收缩压和舒张压水平,治疗前后TNF-α水平;统计2组患者临床疗效。结果:与治疗前比较,治疗后对照组舒张压、收缩压显著降低(P<0.05或P<0.01),观察组显著低于对照组(P<0.01);与治疗前比较,治疗后对照组血清TNF-α水平降低(P<0.05),且观察组显著低于对照组(P<0.01);治疗后对照组有效率82.31%,观察组有效率91.03%,差异有显著统计学意义(P<0.01)。结论:针刺风池穴可显著提高苯磺酸氨氯地平片的降压作用,同时还可降低患者血清TNF-α水平。

English Summary:

To investigate the clinical efficiency of acupuncture on Fengchi (GB 20) point for hypertension and its effect on serum TNF-α level. Methods:A total of 600 cases who came to acupuncture department for residence treatment diagnosed as primary hypertension and complied with the absorbing principles were selected and randomly divided into control group and treatment group, with 300 cases in each group. Control group received amlodipine besylate pill, and treatment group received acupuncture on Fengchi (GB 20) point on the basis of control group. 7 days were 1 treatment course, and 2 groups totally received 2 courses. After the treatment, the systolic and diastolic blood pressure, TNF-α levels and treatment efficiency were compared. Results:Compared with before treatment, the diastolic pressure and systolic pressure of 2 groups decreased significantly after treatment (P<0.05 or P<0.01), and treatment group was lower than control group (P<0.01). Compared with before treatment, the serum TNF-α levels of 2 groups decreased significantly (P<0.05), and treatment group was lower than control group (P<0.01); The effective rate of control group was 82.31%, and the treatment group was 91.03%. The difference between 2 groups was significant (P<0.01). Conclusion:Acupuncture on Fengchi (GB 20) point may improve the decreasing blood pressure of amlodipine besylate pill and ameliorate the serum TNF-α level.

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