Coronary heart disease (CHD) is one of the most common cause of death in the global, and it is a kind of common disease that seriously threats to human health. Integrated traditional Chinese medicine with western medicine is characteristic of Chinese medical system. Combined application of Chinese medicine and western medicine is very common, but the interaction mechanism of that is not very clear. Further studying analysis methods of Chinese and western medicine combined interation in treating CHD to specify the interaction of it can develop new methods of evaluating integrated Chinese and western medicine intervention of clinical efficacy, so as to better guide the clinical standard medication.