| To observe the clinical efficacy of Jianpi Huashi Fang in the treatment of dampness-heat in spleen and stomach type of oral lichen planus (OLP). Methods:A total of 124 patients with dampness-heat in spleen and stomach type of OLP who were treated in our hospital from August 2015 to July 2016 were randomly divided into control group and research group, with 62 cases in each. Control group took transfer factor capsules, and research group took Jianpi Huashi Fang. The TCM symptom score, survival quality, immunoglobulin (immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM)) values, adverse reactions of 2 groups before and after treatment were compared, and clinical efficacy of two groups were evaluated. Results:Compared with pre-treatment, the TCM symptom score, IgG, IgM of 2 groups decreased after treatment, but survival quality scores increased, and above indexes of research group were better than control group (P<0.05); Compared with pre-treatment, the IgA of two groups had no significant difference after treatment (P>0.05); The total effective rate, incidence of adverse reactions in research group were 88.71% (55/62), 3.23% (2/62) respectively, which were better than 74.19% (46/62), 19.35% (12/62) of control group (P<0.05). Conclusion:Jianpi Huashi therapy for treating dampness-heat in spleen and stomach type of OLP can significantly increase clinical efficacy, relieve clinical symptoms, improve immunoglobulin level, promote body recovery, increase survival quality and have less adverse reactions, which has significance of clinical promotion. |
