To observe curative effects of Tongxinluo Capsule combined with western medicine in the treatment of patients with acute myocardial infarction (AMI), and explore the effects on inflammatory factors. Methods: A total of 94 patients with acute myocardial infarction admitted to Xingtai Third Hospital from March 2015 to March 2017 were randomly divided into observation group and control group with 47 cases in each group. The control group was treated with western medicine, and the observation group was treated with Tongxinluo Capsule on the basis of the control group. The course of treatment of the two groups was both 14 days. The therapeutic effects of the two groups were compared. The changes of cardiac function, inflammatory factors and myocardial enzyme before and after treatment were compared. Results: The total effective rate of the observation group (91.49%) was higher than that of the control group (72.34%) (P<0.05). The indicators of stroke volume (SV) and left ventricular ejection fraction (LVEF) increased, and left ventricular end-systolic volume (LVEDV) decreased (P<0.05) of the two groups after treatment; the indicators of SV, LVEF in observation group after treatment were higher than that in the control group and LVEDV was lower than that in the control group (t=6.2713, 5.8286, 12.5245, P<0.05). Tumor necrosis factors (TNF-α) and C-reactive protein (CRP) and interleukin-6 (IL-6) decreased after treatment in two groups (observation group: t=19.3148, 19.7903, 20.5865, control group: t=8.4688, 8.3049, 7.9067, P<0.05); after treatment, TNF-α, CRP and IL-6 of the observation group were lower than those in the control group (t=10.1105, 11.3237, 13.7007, P<0.05). Troponin I (cTnI), creatine kinase (CK) and creatine kinase-MB (CK-MB) decreased after treatment in two groups (observation group: t=19.1719, 84.4794, 86.6657, control group: t=12.8121, 67.6642, 54.6297, P<0.05); after treatment, the indicators of cTnI, CK and CK-MB in observation group were lower than those in the control group (t=9.2587, 22.2531, 13.8418, P<0.05). Conclusion: Tongxinluo Capsule combined with western medicine is effective in the treatment of acute myocardial infarction and can improve the heart function, inflammatory reaction and myocardial enzymes, and has important research value. |